Results 51 to 60 of about 437,042 (308)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Introducing electric spring in the voltage frequency regulation of a multi area multi source integrated power system network

Scientific Reports
The present work demonstrates the application of an electric spring in a multi-source interconnected power system in which coordinated control of frequency and voltage loop is investigated. A two-area power system is considered with non–linearity for the
Debdeep Saha, Soham Dutta
doaj   +1 more source

An Advance Distributed Control Design for Wide-Area Power System Stability [PDF]

, 2013
The development of control of a power system that supply electricity is a major concern in the world. Some trends have led to power systems becoming overstated including the rapid growth in the demand for electrical power, the increasing penetration of ...
Atawi, Ibrahem E
core  

Artificial Neural Network Controller in Two-Area and Five-Area System with Security Attack and Game-Theory Based Defender Action

, 2022
Smart grids are the latest technology to generate and dispatch an optimal amount of power. Thus, there is a need for stability analysis in smart grid systems. If the smart grid is incorporated into the power system, then the phasor measurement unit (PMU)
V. Madhusudhan, R. Kiranmayi, S. Khadarvali   +2 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Load Frequency Control of Renewable Energy Power Systems Based on Adaptive Global Fast Terminal Sliding Mode Control

Applied Sciences
In this paper, the load frequency control (LFC) of multi-area power systems incorporating photovoltaic (PV) and energy storage systems (ESSs) is studied. First, the model of the LFC system encompassing PV and ESS is established.
Jiaming Qian, Xinxin Lv
doaj   +1 more source

Approaching hybridized GWO-SCA based type-II fuzzy controller in AGC of diverse energy source multi area power system

Journal of King Saud University: Engineering Sciences, 2020
The present article addresses robust control of both frequency and tie line power of a two area six unit diverse energy source based non linear power network.
Prakash Chandra Sahu, Ramesh Chandra Prusty, Sidhartha Panda   +2 more
doaj   +1 more source