Results 61 to 70 of about 2,755,308 (302)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

A Scalable Framework for Stylometric Analysis of Multi-author Documents [PDF]

, 2018
Stylometry is a statistical technique used to analyze the variations in the author’s writing styles and is typically applied to authorship attribution problems. In this investigation, we apply stylometry to authorship identification of multi-author documents (AIMD) task. We propose an AIMD technique called Co-Authorship Graph (CAG) which can be used to
Raheem Sarwar, Chenyun Yu, Sarana Nutanong, Norawit Urailertprasert, Nattapol Vannaboot, Thanawin Rakthanmanon   +5 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficient revocable attribute-based encryption scheme

Tongxin xuebao, 2019
In the existing solutions,the time-based scheme is difficult to achieve immediate revocation,and the third-party-based scheme often requires re-encryption,which needs large amount of calculation and doesn’t apply to mas-sive data.To solve the problem,an ...
Xuejun LI, Dan ZHANG, Hui LI
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Fine-grained access control scheme with user privacy protection in cloud storage systems

Tongxin xuebao, 2014
Based on the actual demands of cloud storage system,a new multi-authority ABE (MA-ABE) scheme is constructed to support user privacy protection and attribute revocation.For enhancing efficiency and alleviatingowner’s computing load，the complex computing ...
Min XIAO, Chun-lei WANG, You-sheng ZHOU
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Multi-authority attribute-based encryption access control model for cloud storage

Tongxin xuebao, 2015
The existing attribute-based encryption access control studies are mostly based on single authority,and this scheme is apt to be under attack to cause exposure of secret keys.Thus,a multi-authority access control model PRM-CSAC is proposed.Based on CP ...
Zhi-tao GUAN, Ting-ting YANG, Ru-zhi XU, Zhu-xiao WANG   +3 more
doaj   +2 more sources

Multi-authority security framework for scalable EHR systems [PDF]

International Journal of Medical Engineering and Informatics, 2016
Electronic health record (EHR) systems can be operated in a large-scale distributed environment, such as cloud computing, which might have to be managed by multiple authorities who control the access to patient records. In this way, a large amount of data from patients can be hosted on a large-scale distributed system.
Fatemeh Rezaeibagha, Yi Mu 0001, Willy Susilo, Khin Than Win   +3 more
openaire   +2 more sources