Results 81 to 90 of about 87,489 (286)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Partially hidden policy multi-authority CP-ABE scheme with constant length ciphertext
Tongxin xuebaoTo solve the problems of low security and high resource overhead of existing hidden policy ciphertext policy attribute-based encryption (CP-ABE) schemes, a partially hidden policy multi-authority CP-ABE scheme with constant length ciphertext was proposed.
LIU Yilong, XU Shengwei, YUE Ziyan
doaj +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Bringing Care Governance to Ontario's Retirement Homes Sector
Health Reform Observer - Observatoire des Réformes de Santé, 2019 In 2010, the Ontario government introduced Bill 21, the Retirement Homes Act, 2010 (the Act), which required the licensing of retirement homes (RHs), residents' rights, care and safety standards, inspections, compliance and a newly formed Retirement ...
Blair Roblin +3 more
doaj +1 more source
A Survey on Homomorphic Encryption Schemes: Theory and Implementation
, 2017 Legacy encryption systems depend on sharing a key (public or private) among the peers involved in exchanging an encrypted message. However, this approach poses privacy concerns.
Acar, Abbas +3 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
City strategy : final evaluation [PDF]
, 2011 The City Strategy (CS) concept was first announced in the 2006 Welfare Reform Green Paper – A new deal for welfare: Empowering people to work. CS was designed at a time of growth in the national economy to combat enduring pockets of entrenched ...
Adam, Duncan, Green, Anne E.
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source