Results 51 to 60 of about 5,893,470 (283)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

A Wideband Radial Basis Function Decision Feedback Equaliser Assisted Burst-by-Burst Adaptive Modem

open access: yes, 2002
The performance of radial basis function-based decision feedback equalized (RBF DFE) burst-by-burst adaptive quadrature amplitude modulation (AQAM) is presented for transmissions over dispersive wide-band mobile channels.
Yee, M.S., Hanzo, L.
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

A New Scheme to Generate Multi-Frequency Mm-Wave Signals Based on Cascaded Phase Modulator and I/Q Modulator

open access: yesIEEE Photonics Journal, 2019
We propose a new scheme to generate multi-frequency vector mm-wave signals based on cascaded phase modulator and I/Q modulator by adopting independent-sideband (ISB) modulation scheme.
Mingming Zhao   +6 more
doaj   +1 more source

OFDM signal with BPSK modulated subcarriers for multi-carrier ionospheric sounding [PDF]

open access: yesITM Web of Conferences, 2019
Paper presents the developed algorithm for multi-carrier simultaneous vertical ionospheric sounding by OFDM signal with BPSK modulation of subcarriers.
Ivanov Vladimir   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Fair comparison of complexity between a multi-band CAP and DMT for data center interconnects [PDF]

open access: yes, 2017
We present the first known detailed analysis and fair comparison of complexity of 56-Gb/s Multi-band CAP and DMT over 80-km DCF-free SMF links based on intensity modulation and direct detection (IMDD) for data center interconnects.
Wei, Jinlong   +8 more
core   +1 more source

Bearing fault diagnosis based on multi‐band filtering

open access: yesIET Science, Measurement & Technology, 2022
Bearing is an important part of rotary machinery, which usually operates under a variety of complicated and severe conditions, and is prone to break down.
Yixiang Lu   +4 more
doaj   +1 more source

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