Results 31 to 40 of about 5,893,470 (283)

Polarization-resolved ultrafast all-optical terahertz micro-grating array modulator based on Weyl semimetallic microfilm towards 6G technology

Results in Physics, 2023
The 6th generation (6G) of communication technology, defines 0.1–1 THz as the communication band. As a result, ultrafast modulation and multi-dimensional resolution coding technologies in the terahertz band pose a big challenge.
Min Zhang, Run Chen, Qi Song, Zhongze Peng, Ling Li, Xuejuan Hu, Bingyuan Zhang, Lei Huang, Shuangchen Ruan   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Strong modulation instability in a silicon–organic hybrid slot waveguide [PDF]

, 2015
In this paper, we investigate the strong modulation instability (MI) at telecommunication band in a silicon-organic hybrid slot waveguide. The organic material of polymer poly (bis para-toluene sulfonate) of 2, 4-hexadiyne 1, 6 diol (PTS), which has high
Zhang, Xianting, Yu, Chongxiu, Yan, Binbin, Yuan, Jinhui, Wu, Qiang, Wang, Kuiru, Farrell, Gerald, Sang, Xinzhu, Kang, Zhe   +8 more
core   +1 more source

Photonics-based reconfigurable multi-band linearly frequency-modulated signal generation

Optics Express, 2018
A photonics-based multi-band linearly frequency-modulated (LFM) waveform generator with reconfigurable center frequency, bandwidth and time duration is proposed and demonstrated. By introducing two coherent optical frequency combs (OFCs) with a frequency shift and different free spectral ranges (FSRs) as multi-frequency optical LOs, a set of LFM ...
Wenjuan Chen, Dan Zhu, Chenxu Xie, Tao Zhou, Xin Zhong, Shilong Pan   +5 more
openaire   +2 more sources

Analysis of a Real-Time FSO System Utilizing Xia and SRRC Pulses in Multi-Band Carrier-Less Amplitude and Phase Modulation

IEEE Access
In this paper, we investigate the impact of two pulse shapes on the performance of a real-time free-space optical communication link. The two candidate pulse shapes are the square-root raised cosine and Xia pulse, respectively which are tested as the ...
Paul Anthony Haigh, Mojtaba Mansour Abadi, Zabih Ghassemlooy, Nguyen The Quang, Son Thai Le, Nguyen Tan Hung   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Turbo-Coded Burst-by-Burst Adaptive Wide-Band Speech Transceiver

, 2000
Turbo-coded burst-by-burst adaptive orthogonal frequency division multiplex (AOFDM) wide-band speech transceivers are proposed. A constant throughput adaptive OFDM transceiver was designed and benchmarked against a time-variant rate scheme.
Münster, M., Keller, T., Hanzo, L.
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source