Results 61 to 70 of about 272,036 (281)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
IEEE Access, 2019 We propose and experimentally demonstrate a novel carrier-less amplitude/phase modulation wavelength-division-multiplexing passive optical network (CAP-WDM-PON) with its bandwidth efficiency enhanced by using a multi-band discrete Fourier transform ...
Youxu Zeng +6 more
doaj +1 more source
New Journal of Physics, 2020 A dual-frequency on–off modulator with considerable modulation depth (MD) and relatively low insertion loss (IL) is performed with patterned monolayer graphene metamaterial.
Min Li +8 more
doaj +1 more source
Frequency Domain Multi-Carrier Modulation Based on Prolate Spheroidal Wave Functions
IEEE Access, 2020 A novel frequency domain multi-carrier modulation (MCM-FD) scheme is proposed based on prolate spheroidal wave functions (PSWFs) for reducing the high complexity in the conventional time domain PSWFs multi-carrier modulation (MCM-PSWFs-TD) schemes.
Hongxing Wang +4 more
doaj +1 more source
Baseband analog front-end and digital back-end for reconfigurable multi-standard terminals [PDF]
, 2006 Multimedia applications are driving wireless network operators to add high-speed data services such as Edge (E-GPRS), WCDMA (UMTS) and WLAN (IEEE 802.11a,b,g) to the existing GSM network.
Baschirotto +8 more
core +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Cloud Atlas: Rotational Modulations in the L/T Transition Brown Dwarf Companion HN Peg B [PDF]
, 2018 Time-resolved observations of brown dwarfs' rotational modulations provide powerful insights into the properties of condensate clouds in ultra-cool atmospheres.
Apai, Daniel +13 more
core +4 more sources
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
FPGA implementation of an arbitrary resample rate, FOH, pulse width modulator
The Journal of Engineering, 2019 This study presents a field-programmable gate array implementation of an advanced pulse-width modulator which combines a first-order hold (FOH) with phase accumulator carrier pulse-width modulation (PACPWM) for ...
Mark A. H. Broadmeadow +4 more
doaj +1 more source