Results 101 to 110 of about 1,186,412 (296)

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

Experimental and Numerical Study on the Motion Response of a Hybrid Wind-Wave Energy Platform with Different WEC Arrangements

open access: yes한국해양공학회지
Floating offshore wind turbines (FOWTs) enable large-scale power generation in favorable wind conditions but require platform stability in harsh sea states.
Pyeongsung Jang   +2 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis from ELSA‐Brasil

open access: yesArthritis Care &Research, Accepted Article.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within ELSA‐Brasil included 585 participants (86 RA, 499 controls). Longitudinal analyses were restricted to those
Patrícia Fonseca Estrada   +7 more
wiley   +1 more source

Investigation of Oxygen‐Free Wetting Behavior of Aluminum on Copper via Molecular Dynamics Simulations and Experiments

open access: yesAdvanced Engineering Materials, EarlyView.
The wettability of aluminum droplets (Al) on different copper substrates (Cu), where liquid Al spreads on solid Cu surfaces to form a liquid–solid interface, is studied numerically and experimentally. The experimental and numerical results show good agreement in the fast‐spreading regime.
Shan Lyu   +8 more
wiley   +1 more source

Development of Real-time Remote Driving Simulator based on Multi-body Dynamics [PDF]

open access: yes한국정밀공학회지
Autonomous robots are commonly operated on rough roads. Thus, it is essential to predict their dynamic characteristics. Even though it is possible to use real hardware to acquire a robot’s dynamic characteristics, this requires a significant amount of ...
Suhyun Park   +2 more
doaj   +1 more source

Multi-body Dynamics Simulation by Parallel Computers.

open access: yesTRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C, 1999
The purpose of this study is to establish a technique of solving large scale problems associated with multi-body dynamics simulations and to break through the limitations imposed by traditional methods. It is necessary to compute on a computer, which is fast and has larger memory, for multibody analysis of LSS (Large Space Structure).
Osamu OKAMOTO   +4 more
openaire   +2 more sources

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