Results 191 to 200 of about 3,914,330 (246)

Single‐Cell Dissection of Microglial Dysfunction in Diabetes‐Associated Neurodegenerative Vulnerability

Advanced Science, EarlyView.
Using single‐cell transcriptomic and epigenomic profiling, researchers mapped microglial dysfunction across the lifespan of db/db mice. The authors uncovered a nonlinear microglial remodeling featuring early inflammatory priming, a mid‐stage transcriptional inflection, and late dysfunction.
Jizhou Zhang, Tsz Kwan Yau, Joyce Tse, Tsz Ho Li, Dongjie Hu, Yong Juan Zhao, Ting‐Fung Chan   +6 more
wiley   +1 more source

Structured multi-domain EEG descriptors with phase-based connectivity for lie and truth detection. [PDF]

MethodsX
Surya DU, Pramono SH, Mudjirahardjo P, Muslim MA, Avian C, Rohmatillah M.   +5 more
europepmc   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

Assessing Habitat Suitability and Landscape Connectivity for the Endangered Forest Musk Deer (<i>Moschus berezovskii</i>) at Its Northern Distribution Margin: A Multi-Scale Ensemble Approach. [PDF]

Ecol Evol
Zheng W, Luo P, Li Y, Hai L, Jin X, Qin X, Yan L, Hu D.   +7 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Benchmarking fMRI Denoising Pipelines. [PDF]

Hum Brain Mapp
Zhai T, Gu H, Holton A, Chang E, Frederick BB, Ross TJ, Yang Y, Janes AC.   +7 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

The Further You Are, the Closer You Get: Environmental Similarity Connects Aquatic Invertebrate Communities Across the Terrestrial Landscape in a Large River Network. [PDF]

Ecol Evol
Freedman JW, Kennedy TA, Lytle DA.
europepmc   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Synergies and trade-offs for reaching global biodiversity and climate commitments. [PDF]

Nat Commun
Huang Z, Fang Z, Antonelli A, Silvestro D, Wang J, Tan Y, Li J, Zhou S, Ali M, Lu X, Wang R, Xue S, Zhou Q, Cheng C, Wang Q, Chen H, Bai Y.   +16 more
europepmc   +1 more source