Results 51 to 60 of about 1,347,779 (299)
Realization and Application of Shenwei Simultaneous Multithreading Functional Simulator [PDF]
Jisuanji gongcheng, 2016 imultaneous Multithreading(SMT) allows irrelevant instructions execute synchronously from multiple threads.It achieves the combination of Thread-level Parallelism(TLP) and Instruction-level Parallelism(ILP),enhances the performance of processor further ...
CHEN Weijian,GUO Yong,YIN Fei
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Results in EngineeringAs artificial intelligence advances intensify demands for efficient computing, this article addresses the fundamental limitations of traditional processor power models rooted in empirical frequency/voltage parameters.
Xiaoxuan Peng +4 more
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ESAIR: A Behavior-Based Robotic Software Architecture on Multi-Core Processor Platforms
International Journal of Automation and Smart Technology, 2013 This paper introduces an Embedded Software Architecture for Intelligent Robot systems (ESAIR) that addresses the issues of parallel thread executions on multi-core processor platforms. ESAIR provides a thread scheduling interface to improve the execution
Chin-Yuan Tseng +2 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Adaptive Periodic Thermal Management for Pipelined Hard Real-Time Systems
IEEE Access, 2019 This paper proposes a novel dynamic thermal management approach named Adaptive Periodic Thermal Management (APTM) for multi-core pipelined processors with hard real-time constraints. During online execution, the approach optimizes the peak temperature of
Long Cheng +4 more
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