Results 61 to 70 of about 1,347,779 (299)

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Optimization of the Load Balancing Policy for Tiled Many-Core Processors

IEEE Access, 2019
Tiled many-core processors (i.e., KNL and the TILE-Gx72 processor), on which processing cores are fitted onto a single chip and cores are interconnected via mesh-based networks, are different from the traditional many-core systems. Their operating system
Ye Liu, Shinpei Kato, Masato Edahiro
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Energy-Efficient Control of Mobile Processors Based on Long Short-Term Memory

IEEE Access, 2019
Smartphones that are equipped with high-clock frequency and multi-core processors are being commercially released to provide various services. As the number of cores and the clock speed of a mobile processor increases, its power consumption also ...
Jaehwan Lee, Sanghyuck Nam, Sangoh Park
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Energy-efficient Task Scheduling on Heterogeneous Multicore Real-time Systems with Synchronization [PDF]

Jisuanji kexue
The research on energy-efficient scheduling of synchronous tasks in multi-core real-time systems mainly focuses on homogeneous multi-core processor platforms.The architecture of heterogeneous multi-core processors can more effectively exert the system ...
ZHAO Xiaosong, HUANG Chao, LI Jian, KANG Yulong
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Processors Allocation for MPSoCs With Single ISA Heterogeneous Multi-Core Architecture

IEEE Access, 2017
Single-instruction set architecture (ISA) heterogeneous multi-processor architecture is promising for developing multi-processor system-on-chips (MPSoCs). In this architecture, all processors execute the same instruction set, yet with various performance
Yi-Jung Chen, Wen-Wei Chang, Chia-Yin Liu, Cheng-En Wu, Bo-Yuan Chen, Ming-Ying Tsai   +5 more
doaj   +1 more source