Results 41 to 50 of about 913,882 (280)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Multi-Criteria and Multi-Stage Facility Location Selection under Interval Type-2 Fuzzy Environment: A Case Study for a Cement Factory [PDF]

open access: yesInternational Journal of Computational Intelligence Systems, 2015
The study proposes a comprehensive and systematic approach for multi-criteria and multi-stage facility location selection problem. To handle with high and more uncertainty in the evaluation and selection processes, the problem is solved by using multi ...
Ferhan Cebi, İrem Otay
doaj   +1 more source

Decomposition Methods for the Network Optimization Problem of Simultaneous Routing and Bandwidth Allocation Based on Lagrangian Relaxation

open access: yesEnergies, 2022
The main purpose of the work was examining various methods of decomposition of a network optimization problem of simultaneous routing and bandwidth allocation based on Lagrangian relaxation.
Ihnat Ruksha, Andrzej Karbowski
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Application of Multi-Criteria Decision Analysis Techniques for Informing Select Agent Designation and Decision Making

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
The Centers for Disease Control and Prevention (CDC) Select Agent Program establishes a list of biological agents and toxins that potentially threaten public health and safety, the procedures governing the possession, utilization, and transfer of those ...
Segaran P. Pillai   +6 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Multiple Criteria Decision Making Penentuan Juara Lomba Roasting Kopi Menggunakan Multi-Attributive Border Approximation Area Comparison

open access: yesJurnal Ilmiah Computer Science
Multiple Criteria Decision Making (MCDM) is an approach used to evaluate and select alternatives based on several criteria or factors. The purpose of this study is to apply the Multi-Attributive Border Approximation Area Comparison (MABAC) method in ...
Sanriomi Sintaro
doaj   +1 more source

Getting efficient choices in buildings by using Genetic Algorithms: Assessment & validation

open access: yesOpen Engineering, 2019
The energy consumption in buildings, can be reduced through a rational choice of the household appliances to be acquired. This choice can be based, on a specific criteria, settled according to the consumer needs.
Santos Ricardo Simões   +2 more
doaj   +1 more source

Priority Events Determination For The Risk-oriented Management Of Electric Power System [PDF]

open access: yes, 2018
The task of risk-oriented management of the electric power system in conditions of multi-criteria choice is considered. To determine the most effective measures, the implementation of which will reduce the magnitude of the risk of an emergency situation,
Kosterev, M. (Mykola)   +1 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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