Results 41 to 50 of about 964,214 (297)

Multi-criteria Anomaly Detection using Pareto Depth Analysis [PDF]

, 2012
We consider the problem of identifying patterns in a data set that exhibit anomalous behavior, often referred to as anomaly detection. In most anomaly detection algorithms, the dissimilarity between data samples is calculated by a single criterion, such ...
Calder, Jeff, Hero III, Alfred O., Hsiao, Ko-Jen, Xu, Kevin S.   +3 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-criteria decision-making for solving transport sustainability issues: an overview

Transport
With the recognition of the impact of the transport sector on climate change and human health, decision-makers are under the pressure to shape the transport sector in a more sustainable way, considering more sustainable options and technologies. Besides
Indrė Šikšnelytė-Butkienė, Dalia Štreimikienė, Tomas Baležentis, Leonardo Agnusdei   +3 more
doaj   +1 more source

Applying multi-criteria optimisation to develop cognitive models [PDF]

, 2005
A scientific theory is developed by modelling empirical data in a range of domains. The goal of developing a theory is to optimise the fit of the theory to as many experimental settings as possible, whilst retaining some qualitative properties such as ...
Gobet, F, Lane, PCR
core  

Three Perspectives on Motivation and Multi-Criteria Assessment of Organic Food Systems [PDF]

, 2013
The complexity of values related to organic food systems is normally difficult to ascertain, understand and act upon for both producers and consumers, as well as for other agents.
Alrøe, Hugo Fjelsted, Christensen, Tove, Dubgaard, Alex, Kastberg, Peter, Kærgård, Niels, Ljungdalh, Anders, Læssøe, Jeppe, Noe, Egon, Olsen, Søren Bøye   +8 more
core   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Variational Autoencoders-Based Algorithm for Multi-Criteria Recommendation Systems

Algorithms
In recent years, recommender systems have become a crucial tool, assisting users in discovering and engaging with valuable information and services. Multi-criteria recommender systems have demonstrated significant value in assisting users to identify the
Salam Fraihat, Qusai Shambour, Mohammed Azmi Al-Betar, Sharif Naser Makhadmeh   +3 more
doaj   +1 more source

Long-Term Electricity Scenarios for the MENA Region: Assessing the Preferences of Local Stakeholders Using Multi-Criteria Analyses

Energies, 2019
In recent years, most countries in the Middle East and North Africa (MENA), including Jordan, Morocco and Tunisia, have rolled out national policies with the goal of decarbonising their economies.
Ole Zelt, Christine Krüger, Marina Blohm, Sönke Bohm, Shahrazad Far   +4 more
doaj   +1 more source

Multi-criteria analysis applied to multi-objective optimal pump scheduling in water systems [PDF]

, 2019
This work presents a multi-criteria-based approach to automatically select specific non-dominated solutions from a Pareto front previously obtained using multi-objective optimization to find optimal solutions for pump control in a water supply system ...
Brentan Bruno, Carpitella Silvia, Certa Antonella, Izquierdo Joaquín, Montalvo Idel   +4 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source