Results 81 to 90 of about 4,409,486 (310)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

MULTI-CRITERIA ANALYSIS OF FACTORS USE LEVEL: THE CASE OF WATER FOR IRRIGATION [PDF]

open access: yes
In this paper we present a methodology to analyse input use in the agricultural sector. The novelty of the theoretical model explained is that it has been developed considering a multi-criteria environment.
Gomez-Limon, Jose Antonio   +2 more
core   +1 more source

Mapping Forest Fire Risk and Development of Early Warning System for NW Vietnam Using AHP and MCA/GIS Methods

open access: yesApplied Sciences, 2020
Forest fires constitute a major environmental problem in tropical countries, especially in the context of climate change and increasing human populations.
Thanh Van Hoang   +8 more
doaj   +1 more source

Multi-Criteria Decision Making Using Bayesian Networks

open access: yes, 2022
In this thesis, we examine how to represent and combine the utilities elicited from multiple experts across multiple interdependent and uncertain criteria.
ABIDA SHAHZAD (12345985)
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Social Multi-Criteria Evaluation (SMCE) [PDF]

open access: yes
The main argument developed here is the proposal of the concept of “Social Multi-Criteria Evaluation” (SMCE) as a possible useful framework for the application of social choice to the difficult policy problems of our Millennium, where, as stated by ...
Giuseppe Munda
core  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

6-DOFs Robot Placement Based on the Multi-Criteria Procedure for Industrial Applications

open access: yesRobotics
Robot acceptance is rapidly increasing in many different industrial applications. The advancement of production systems and machines requires addressing the productivity complexity and flexibility of current manufacturing processes in quasi-real time ...
Francesco Aggogeri, Nicola Pellegrini
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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