Results 71 to 80 of about 2,759,056 (299)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Using multi-criteria analysis for smart city assessment

Cidades, Comunidades e Território, 2022
Urban centers have been under a new concept of city. Smart Cities are, in a nutshell, organized communities that feature high communication technology and conscious investments in sustainability, providing dynamic and safe environments.
Daiane Maria De Genaro Chiroli, Érica A. B. Solek, Rosana S. Oliveira, Bertiene M. L. Barboza, Rodolfo P. de Campos, João L. Kovaleski, Sérgio M. Tebecherani, Flavio Trojan   +7 more
doaj  

The evaluation of the II Pillar pension’s funds: an integrated approach using multi-criteria decision methods

Business: Theory and Practice, 2017
Lithuania has had a significant reform path in the last twenty-five years like other communist bloc countries during the intense changes in the world. Changes and transformations took place in various areas including social security system.
Lina Novickytė, Viktorija Rabikauskaitė   +1 more
doaj   +1 more source

A Methodology for the Selection of Multi-Criteria Decision Analysis Methods in Real Estate and Land Management Processes [PDF]

, 2018
Real estate and land management are characterised by a complex, elaborate combination of technical, regulatory and governmental factors. In Europe, Public Administrators must address the complex decision-making problems that need to be resolved, while ...
Battisti, Fabrizio, Chiovitti, Anthea, Guarini, Maria Rosaria   +2 more
core   +3 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Evaluation of antiarrhythmia drug through QSPR modeling and multi criteria decision analysis

Scientific Reports
This study explores how topological indices (TIs), which are mathematical descriptors of a drug’s molecular structure, can support to predict vital properties and biological activities. This understanding is a key for more effective drug design.
Shereen Iqbal, Hifza Iqbal, Muhammad Akhtar Tarar, Muhammad Farhan Hanif, Osman Abubakar Fiidow   +4 more
doaj   +1 more source

A bibliometric data analysis of multi-criteria decision making methods in heritage buildings

Journal of Civil Engineering and Management, 2019
Numerous countries are trying to find the best solution for conservation, restoration or reuse of the heritage buildings, preserving their cultural, historical, ethnic and spiritual values.
ŽydrÅ«nÄ— MorkÅ«naitÄ—, Darius Kalibatas, Diana KalibatienÄ—   +2 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Flue gas treatment multi-criteria analysis

Energy Procedia, 2017
Abstract Energy is the main factor effecting national economies of countries, therefore it is in everyone’s best interest to improve energy efficiency. One way to do that is by developing and implementing heat recovery from industrial processes, rather than creating waste heat in industry. There are different technologies available for heat recovery,
Jevgenijs Selivanovs, Edgars Vigants, Vivita Priedniece, Ivars Veidenbergs, Dagnija Blumberga   +4 more
openaire   +1 more source