Results 111 to 120 of about 9,608,487 (304)

A Multi-Criteria Assessment Strategy for 3D Printed Porous Polyetheretherketone (PEEK) Patient-Specific Implants for Orbital Wall Reconstruction. [PDF]

open access: yesJ Clin Med, 2021
Sharma N   +7 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Prioritizing Emerging Zoonoses in The Netherlands [PDF]

open access: yes, 2010
Background: To support the development of early warning and surveillance systems of emerging zoonoses, we present a general method to prioritize pathogens using a quantitative, stochastic multi-criteria model, parameterized for the Netherlands ...
van der Giessen, J.W.B.   +105 more
core   +5 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Approximate Equilibria for Bayesian Multi-Criteria Games [PDF]

open access: yes
AMS Classification: 91A10non-cooperative games;Bayesian multi-criteria ...
Tijs, S.H., Mallozzi, L., Pusillo, L.
core  

Understanding the rules of the game: marking peer assessment as a medium for developing students' conceptions of assessment [PDF]

open access: yes, 2004
Students need to understand assessment processes in order to succeed in higher education. However, recent research has identified how difficult it is for students to become absorbed into the assessment culture of their disciplines, with a recognition ...
Bloxham, Susan   +4 more
core   +1 more source

Comparative Analysis of Choroid Plexus Volume Between MOG Antibody Associated Disease and Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Choroid plexus volume (CPV) has been proposed as a neuro‐immunological marker of multiple sclerosis (MS), but its relevance in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) remains uncertain. We analyzed CPV in 43 individuals with MOGAD, 48 with MS, and 44 healthy controls using a Bayesian Gaussian mixture modeling ...
Jae‐Won Hyun   +4 more
wiley   +1 more source

Optimization Library for Interactive Multi-Criteria Optimization Tasks [PDF]

open access: yes, 2012
The commercial library Optimization 2.1 for interactive multi-criteria optimization tasks has been released along with Dymola 2013. The library offers several numerical optimization algorithms for solving different kinds of optimization tasks.
Pfeiffer, Andreas, Andreas Pfeiffer
core   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad   +22 more
wiley   +1 more source

Arctic Ocean Acidification Assessment: Summary for Policymakers [PDF]

open access: yes, 2013
Executive summary of the 2013 Arctic Ocean Acidification Assessment, including an update on the state of ocean acidification in the Arctic and how that acidification is impacting on the Arctic marine environment. It outlines each of the ten key findings
Arctic Monitoring and Assessment Programme
core  

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