Multi-criteria Decision Analysis for Assessing Orphan Drugs
The assessment of new medicinal treatments usually includes cost-effective analyses which estimate the efficacy of the drug, its safety, health-related quality of life benefits and the cost. This is a comparative process where a new drug is assessed in comparison to the existing treatments for that disease. In the event that there is no treatment, then
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Soft Computing-based New Interval-valued Pythagorean Triangular Fuzzy Multi-criteria Group Assessment Method without Aggregation: Application to a Transport Projects Appraisal [PDF]
M. Aghamohagheghi +2 more
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Environmentally Extended Input–Output Analysis of the UK Economy: Key Sector Analysis [PDF]
The paper assesses the sustainability of investment in various economic sectors, with the aim of minimizing resource use and generation of emissions. The broad development focus of the paper and the potential for the proposed methodology to be applied in
Shmelev, Stanislav Edward
core +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Multi-Criteria Data Quality Assessment Maintenance perspective
Godkänd; 2014; 20140619 (andbra)
Al-Jumaili, Mustafa +2 more
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Assessing alimony rights violations: a neutrosophic multi-criteria evaluation
This study addressed the violations of child support rights in the province of Pichincha, employing a Multi-Criteria Decision-Making (MCDM) methodology based on the TODIM and PROMETHEE methods in conjunction with neutrosophic theory. The research aimed to identify critical failures in the child support administration system within the study area.
Montenegro Altamirano, Vanessa Lisseth +2 more
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Water Quality Assessment using GIS based Multi-criteria evaluation (MCE) and Analytical Hierarchy Process (AHP) Methods in Yenagoa Bayelsa State, Nigeria [PDF]
Eteh Desmond Rowland +4 more
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Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
ENHANCING SUSTAINABILITY ASSESSMENT OF BRIDGES IN AGGRESSIVE ENVIRONMENTS THROUGH MULTI-CRITERIA GROUP DECISION-MAKING [PDF]
Ignacio J. Navarro +2 more
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