Results 121 to 130 of about 1,857,953 (354)

Multi-criteria Decision Analysis for Assessing Orphan Drugs

open access: yes, 2022
The assessment of new medicinal treatments usually includes cost-effective analyses which estimate the efficacy of the drug, its safety, health-related quality of life benefits and the cost. This is a comparative process where a new drug is assessed in comparison to the existing treatments for that disease. In the event that there is no treatment, then
openaire   +1 more source

Environmentally Extended Input–Output Analysis of the UK Economy: Key Sector Analysis [PDF]

open access: yes
The paper assesses the sustainability of investment in various economic sectors, with the aim of minimizing resource use and generation of emissions. The broad development focus of the paper and the potential for the proposed methodology to be applied in
Shmelev, Stanislav Edward
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Multi-Criteria Data Quality Assessment Maintenance perspective

open access: yes, 2014
Godkänd; 2014; 20140619 (andbra)
Al-Jumaili, Mustafa   +2 more
openaire   +2 more sources

Assessing alimony rights violations: a neutrosophic multi-criteria evaluation

open access: yesJournal of Fuzzy Extension and Applications
This study addressed the violations of child support rights in the province of Pichincha, employing a Multi-Criteria Decision-Making (MCDM) methodology based on the TODIM and PROMETHEE methods in conjunction with neutrosophic theory. The research aimed to identify critical failures in the child support administration system within the study area.
Montenegro Altamirano, Vanessa Lisseth   +2 more
openaire   +2 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy