Results 51 to 60 of about 559,365 (305)

Multi-Criteria Decision-Making in Software Production [PDF]

, 2020
Decision making is an inevitable part of software engineering. Software engineers make a considerable number of decisions during the software development life cycle. Thus, as a subset of software engineering, software production can be considered a continuous decision-making process.
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Triangular fuzzy merec (TFMEREC) and its applications in multi criteria decision making [PDF]

Journal of Fuzzy Extension and Applications
This paper presents a proposed method, Triangular Fuzzy MEREC (TFMEREC), which combines Triangular Fuzzy Numbers (TFNs) and Method Based on The Removal Effects of Criteria (MEREC).
Qaiyyum Hafizi Hasnan, Zahari Rodzi, Nor Hanimah Kamis, Faisal Al-Sharqi, Ashraf Al-Quran, Mamika Ujianita Romdhini   +5 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Development, test and comparison of two Multiple Criteria Decision Analysis(MCDA) models: A case of healthcare infrastructure location [PDF]

, 2015
When planning a new development, location decisions have always been a major issue. This paper examines and compares two modelling methods used to inform a healthcare infrastructure location decision. Two Multiple Criteria Decision Analysis (MCDA) models
Bamford, D, Bamford, David, Dehe, B, Dehe, Benjamin   +3 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Multi-Criteria Decision Making Using Bayesian Networks

, 2022
In this thesis, we examine how to represent and combine the utilities elicited from multiple experts across multiple interdependent and uncertain criteria.
ABIDA SHAHZAD (12345985)
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Multi-criteria Decision Making with Fuzzy Targets [PDF]

, 2007
This paper discusses the issue of how to solve multi-criteria decision making (MCDM) problems from the target perspective. In particular, instead of making use of the traditional normalization method, it tries to calculate the probability of meeting some
Nakamori, Yoshiteru, Yan, Hongbin, Huynh, Van-Nam   +2 more
core  

Deforestation Risk Zoning Using Analytical Hierarchy Process

جغرافیا و پایداری محیط, 2020
This study aimed to identify the most influential factors in deforestation using multi-criteria decision-making method in a part of northern Zagros forests in Iran with a total area of 9177 hectares.
Hiva Mahmoudi, Mahtab Pir Bavaghar, Parviz Fatehi   +2 more
doaj   +1 more source