Results 61 to 70 of about 1,234,846 (256)

Mapping of multiple criteria for priority setting of health interventions: an aid for decision makers

open access: yesBMC Health Services Research, 2012
Background In rationing decisions in health, many criteria like costs, effectiveness, equity and feasibility concerns play a role. These criteria stem from different disciplines that all aim to inform health care rationing decisions, but a single ...
Tromp Noor, Baltussen Rob
doaj   +1 more source

The development of a multi-criteria decision analysis aid to help with contraceptive choices: My Contraception Tool.

open access: yes, 2013
My Contraception Tool (MCT) applies the principles of multi-criteria decision analysis to the choice of contraceptive method. Its purpose is to make the decision-making process transparent to the user and to suggest a method to them based on their own ...
Cowan, Frances M   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Evaluation of antiarrhythmia drug through QSPR modeling and multi criteria decision analysis

open access: yesScientific Reports
This study explores how topological indices (TIs), which are mathematical descriptors of a drug’s molecular structure, can support to predict vital properties and biological activities. This understanding is a key for more effective drug design.
Shereen Iqbal   +4 more
doaj   +1 more source

Revealed preferences towards the appraisal of orphan drugs in Poland - multi criteria decision analysis

open access: yesOrphanet Journal of Rare Diseases, 2018
Background A Multi Criteria Decision Analysis (MCDA) technique was adopted to reveal the preferences of the Appraisal Body of the Polish HTA agency towards orphan drugs (OMPs).
Katarzyna Kolasa   +4 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Implementation of eunethta core model (R) in lombardia: the VTS Framework [PDF]

open access: yes, 2014
Objectives: This study describes the health technology assessment (HTA) framework introduced by Regione Lombardia to regulate the introduction of new technologies.
Alberto, Strada   +5 more
core   +2 more sources

Taxonomical analysis of regional development by outranking relations on multiple principal components [PDF]

open access: yes
This paper proposes a method of ranking the elements of a set of objects by multi-criteria analysis on multiple principal components derived from a multiple variable dataset pertaining to the objects.
Mishra, SK
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Spatial multi-criteria decision analysis for safe school site selection [PDF]

open access: yes, 2010
Schools which are located in a strategic and safe area play an important role in improving students’ performance and excellence. To ensure both success and long -term sustainability of the school planning,the finding of suitable sites ...
Ahmad, Noordin   +2 more
core  

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