Results 61 to 70 of about 1,383,489 (294)

A holistic multi-methodology for sustainable renovation [PDF]

, 2018
A review of the barriers for building renovation has revealed a lack of methodologies, which can promote sustainability objectives and assist various stakeholders during the design stage of building renovation/retrofitting projects.
Aliakbar Kamari, Bammer, G., Bertalanffy, L. von, Bhaskar, R. A., Boeri, A., Checkland, P., Checkland, P., Checkland, P., Churchman, C., Churchman, C. W., Cross, N., Dallas, M., Degan, G., Denzin, N., Dorst, K., Estkowski, T., Groat, L., Habermas, J., Hillier, F. S., Jackson, M. C., Jayaratna, N., Kamari, A., Kamari, A., Kamari, A., Kamari, A., Kamari, A., Keeney, R. L., Linstow, H. A., Mason, R., McNamara, C., Mitroff, I. I., Näegeli, C., Petkov, D., Poul Henning Kirkegaard, Rossella Corrao, Saaty, T. L., Schunck, C., Simon, H. A., Simonsen, J., Stina Rask Jensen, Triantaphyllou, E., Vo, H. V., Weinberg, G. M., Woyseth, H.   +43 more
core   +4 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Explaining Results of Multi‐Criteria Decision‐Making

Journal of Multi-Criteria Decision Analysis
ABSTRACTTransparency in computing is an important precondition to ensure the trust of users. One concrete way of delivering transparency is to provide explanations of computing results. To this end, we introduce a method for explaining the results of various linear and hierarchical multi‐criteria decision‐making (MCDM) techniques such as the weighted ...
Martin Erwig, Prashant Kumar
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Analysis of Production and Location Decisions by Means of Multi-Criteria Analysis [PDF]

, 1979
During the last few years economists and operations researchers have paid much attention to multi-criteria analysis as a tool in modern decision-making.
Atkinson, Benayoun, Bilkey, Bronsema, Callahan, Charnes, Charnes, Charnes, Charnes, Charnes, Charnes, Charnes, Chateau, Cyert, Delft, Dyer, Edmund, Fichefet, Fishburn, Forsyth, Geoffrion, Goodman, Haimes, Hawkins, Hilgard, Hill, Ignizio, Ignizio, Ijiri, Jaap Spronk, Jacquet-Lagrèze, Johnsen, Jääskeläinen, Jääskeläinen, Kahne, Keeney, Killough, Kornbluth, Lane, Lee, Lee, Lee, Lee, Lee, March, McGuire, Monarchi, Nijkamp, Nijkamp, Nijkamp, Nijkamp, Nijkamp, Osteryoumg, Paelinck, Paelinck, Peter Nijkamp, Philippatos, Price, Roy, Ruefli, Salkin, Sartoris, Schimpeler, Schlager, Spliid, Theil, Wallenius, Wilhelm, Zeleny   +68 more
core   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Penggunaan Algoritma Multi Criteria Decision Making dengan Metode Topsis dalam Penempatan Karyawan

Jurnal EECCIS (Electrics, Electronics, Communications, Controls, Informatics, Systems), 2015
The employees are a major asset in the company so that the company can operate properly. In employees pacement, often a mismatch between the positions of the competence of employees.
Agung N. Pramudhita, Hadi Suyono, Erni Yudaningtyas   +2 more
doaj   +1 more source

A study product design of optimal solution for customer requirements [PDF]

, 2015
In this paper, the author uses an evaluative criteria model and their associated criteria status, product evaluative criteria software of results and product objective function of optimal values solution, along with product morphological analysis, to ...
LIAO, Shih-Chung
core   +2 more sources

Multi‐criteria decision making in creative problem solving

Kybernetes, 2013
PurposeThe purpose of this paper is to present the adapted model per phases of the creative problem solving (CPS) process, where multi‐criteria decision making (MCDM) methods are used in the decision‐making phase. Also, to adapt and complete the steps of the six‐question technique, in order to establish the criteria's importance.Design/methodology ...
Čančer, Vesna, Mulej, Matjaž
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source