Results 51 to 60 of about 457,615 (216)

The evaluation of Ecosystem Services production: an application in the Province of Ferrara

Bio-based and Applied Economics, 2015
This paper presents an evaluation of the provision of Ecosystem Services (ES). The analysis is based on the design of a framework suitable to be translated into a multi-criteria evaluation process, followed by empirical testing.
Parthena Chatzinikolaou, Davide Viaggi, Meri Raggi   +2 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Multi-criteria and econometric evaluation of dairy products

Mljekarstvo, 2014
This study examined the multi-criteria assessment of four dairy products: “Pomursko mlejko” (Pomurje milk), “Lejko mleko” (light milk), “Fyto mleko” (Fyto milk) and “Posneto mleko v prahu” (dried milk). The research was executed by using a multi-criteria
Karmen Pažek, Jernej Turk , Sebjan Hari , Črtomir Rozman, Jernej Prišenk   +4 more
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Single-objective and multi-objective optimization using the HUMANT algorithm

Croatian Operational Research Review, 2015
When facing a real world, optimization problems mainly become multi-objective i.e. they have several criteria of excellence. A multi-criteria problem submitted for multi-criteria evaluation is a complex problem, as usually there is no optimal solution ...
Marko Mladineo, Ivica Veža, Nikola Gjeldum   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Establishing a Spatial Database for Decision-Making in the Identification of Rural Development Centers - Case Study "Babil Governorate"

Maǧallaẗ al-baṣraẗ al-ʻulūm al-zirāʻiyyaẗ
The establishment of a spatial database to evaluate planning processes and measure suitability and development contributes to supporting decision-making in identifying appropriate centers for rural development.
Rasha Q. Luaibi, Mustafa A. Ibrahim
doaj   +3 more sources