Results 51 to 60 of about 602,223 (293)

Definition of criteria and alternatives for choosing the optimal mining method deposits when applying multi: Criteria optimization [PDF]

open access: yesPodzemni Radovi
When solving real problems, and to make a quality decision, it is necessary to consider a great number of often complex parameters. For these reasons, the development of decision-making process modeling has seen significant growth in recent years, and ...
Bajić Sanja   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Preference-Based Search and Multi-Criteria Optimization [PDF]

open access: yesAnnals of Operations Research, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Differential Inequalities in Multi-Agent Coordination and Opinion Dynamics Modeling [PDF]

open access: yes, 2017
Distributed algorithms of multi-agent coordination have attracted substantial attention from the research community; the simplest and most thoroughly studied of them are consensus protocols in the form of differential or difference equations over general
Cao, Ming, Proskurnikov, Anton V.
core   +3 more sources

Multi-criteria optimization in a methanol process

open access: yesApplied Thermal Engineering, 2009
Abstract Opportunities for additional profit in retrofits depend very much on the existing plant structure, its parameters and energy system. Combined production of heat flow rate, power and chemical products can improve process efficiency. This paper presents an application of the nonlinear programming (NLP) optimization techniques, including ...
Kovač Kralj, Anita, Glavič, Peter
openaire   +3 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Neuro-Evolutionary Synthesis of Game Models of Control under Uncertainty Based on Distributed Computing Technology

open access: yesEngineering Proceedings, 2023
The methodology basic principles of the neuro-evolutionary synthesis of multi-object multi-criteria systems control models under conflict and uncertainty in real time are discussed.
Vladimir A. Serov   +3 more
doaj   +1 more source

A multi-criteria optimization and decision-making approach for improvement of food engineering processes. [PDF]

open access: yes, 2013
The objective of this study was to propose a multi-criteria optimization and decision-making technique to solve food engineering problems. This technique was demostrated using experimental data obtained on osmotic dehydratation of carrot cubes in a ...
Abakarov, Alik   +2 more
core   +6 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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