Results 51 to 60 of about 350,054 (265)
Energies, 2020 Efficiency measures and the integration of renewable energy sources are key to achieving a sustainable society. The cumulative exergy consumption describes the resource consumption of a product from the raw material to the final utilisation.
Lukas Kriechbaum +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Energies, 2022 The popularity of electric vehicles (EVs) is increasing day by day due to their environmentally friendly operation and high milage as compared to conventional fossil fuel vehicles.
Amad Ali +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Load-flow model of a multi-energy system [PDF]
E3S Web of Conferences, 2019 Current trends in the energy development includes the creation of multi-energy systems (MES) with several energy carriers that are planned, designed and operated with essential coordination of their subsystems. When managing the development and functioning of such systems, optimization problems should be solved to minimize the cost of production ...
Efimov Dmitry, Bykov Dmitry
openaire +2 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Applications of jet–jet/film impingement for atomization enhancement
Frontiers in PhysicsThis mini-review mainly focuses on the fundamental problem of jet–jet/film impingement exhibiting superior fragmentation and atomization characteristics compared to single-jet injection; this has been widely used in agricultural irrigation and combustion
Chengming He +4 more
doaj +1 more source
Frontiers in Energy Research, 2023 The inherent intermittency of high-penetrated renewable energy poses economic and reliable issues of microgrid energy management. This study proposes a two-layer predictive energy management system (PEMS) for high-renewable multi-energy microgrid (MEM ...
Da Xu +8 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source