Results 181 to 190 of about 36,032 (319)

A recurrent neural network for soft sensor development using CHO stable pools in fed‐batch process for SARS‐CoV‐2 spike protein production as a vaccine antigen

Biotechnology Progress, EarlyView.
Abstract Fed‐batch recombinant therapeutic protein (RTP) production processes utilizing Chinese Hamster Ovary (CHO) cells can take a long period of time (>10 days). Within this period, not all critical features may be measured routinely, and in fact, some are only measured once the process is terminated, complicating decision making.
Sebastian‐Juan Reyes, Robert Voyer, Yves Durocher, Olivier Henry, Phuong Lan Pham   +4 more
wiley   +1 more source

Design of a novel multi-epitope vaccine candidate against Yersinia pestis using advanced immunoinformatics approaches: An in silico study

Biochemistry and Biophysics Reports
Yersinia pestis is the perilous pandemics that occurred in Asia and Europe. The bacterium has shown drug resistance that can cause the future pandemic and destroy the drug treatment against plague.
Mohamed J. Saadh, Hanan Hassan Ahmed, Radhwan Abdul Kareem, Lalji Baldaniya, Lokesh Verma, G.V. Siva Prasad, Mamata Chahar, Waam Mohammed Taher, Mariem Alwan, Mahmood Jasem Jawad, Atheer Khdyair Hamad   +10 more
doaj  

Immunoinformatics Design of Novel Multi-Epitope Subunit Vaccine for SARS-CoV-2 by Exploring Virus Conserved Sequences of the Spike Glycoproteins [PDF]

, 2020
Itemobong S. Ekaidem, Anietie Moses, Youtchou Mirabeau Tatfeng   +2 more
openalex   +1 more source

In silico design of a multi-epitope peptide construct as a potential vaccine candidate for Influenza A based on neuraminidase protein [PDF]

, 2021
Mandana Behbahani, Mohammad Moradi, Hassan Mohabatkar   +2 more
openalex   +1 more source

Combating cancer immunotherapy resistance: a nano‐medicine perspective

Cancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong, Xintong Xie, Juan Wu, Xiangyu Wang, Wenxiang Zhang, Shuowen Wang, Daria Valerievna Abbasova, Yi Fang, Hongnan Jiang, Jidong Gao, Jing Wang   +10 more
wiley   +1 more source

Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine

, 2015
Liliane Maria Fernandes de Oliveira, Mirian Galliote Morale, Ana Amélia Macedo Chaves, Aline Marques Cavalher, Aline Soriano Lopes, Mariana O. Diniz, Alessandra Soares‐Schanoski, Robson L. Melo, Luís Carlos de Souza Ferreira, Maria Leonor S. Oliveira, Marilene Demasi, Paulo Lee Ho   +11 more
openalex   +2 more sources

Multi-epitope Folate Receptor Alpha-loaded Dendritic Cell Vaccine [PDF]

, 2020

openalex   +1 more source

A Novel Design of Multi-epitope Vaccine Against Helicobacter pylori by Immunoinformatics Approach [PDF]

, 2021
Junfei Ma, Jingxuan Qiu, Shuying Wang, Qianyu Ji, Dongpo Xu, Haiwang Wang, Zhiguang Wu, Qing Liu   +7 more
openalex   +1 more source

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

Chemistry &Biodiversity, EarlyView.
ABSTRACT Cancer is a major global health concern. Therefore, new treatment options are needed. The phytochemicals have different chemical structures. It also exhibits several other biological activities. Therefore, these compounds are promising anticancer agents. This review aims to identify and assess new candidates for anticancer therapy. Researchers
Alaa A. A. Aljabali, Mohammad A. Obeid, Rasha M. Bashatwah, Esam Qnais, Omar Gammoh, Abdelrahim Alqudah, Vijay Mishra, Yachana Mishra, Mohammad Ahmed Khan, Suhel Parvez, Mohamed El‐Tanani, Taher Hatahet   +11 more
wiley   +1 more source

Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions

Cancer Nexus, EarlyView.
ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley   +1 more source