Results 231 to 240 of about 79,223 (384)

In silico design of a multi-epitope vaccine against the triple negative breast cancer. [PDF]

Sci Rep
Zahraei M, Roohparvar Basmenj E, Behrouzi G, Heidari Keshel S, Alem M.   +4 more
europepmc   +1 more source

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

Animal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao, Ming Zhong, Wenjiang Zheng, Zhendong Guo, Ye Zhou, Qiuhong Li, Lijuan Qiu, Liangwen Yu, Haishan Long, Geng Li   +9 more
wiley   +1 more source

Rational design of multi-epitope vaccine for Chandipura virus using an immunoinformatics approach. [PDF]

PLoS One
Naderian R, Ahmad S, Rahmanian M, Aghaamoo S, Rahbar A, Pajand O, Alizadeh A, Nazarian S, Sanami S, Eslami M.   +9 more
europepmc   +1 more source

Multimorbidity and animal models

Animal Models and Experimental Medicine, EarlyView.
Multimorbidity, defined as the coexistence of ≥2 chronic conditions, is associated with aging, genetics, and environmental factors. Animal models in multimorbidity research span three tiers: simple organisms for initial screening → rodents for mechanistic analysis → large mammals for clinical prediction.
Xinpei Wang, Yakun Ren, Xingjiu Yang, Mengyuan Li, Junxiu Liu, Xiaoyan Du, Wen Wang, Ran Gao   +7 more
wiley   +1 more source

Reverse vaccinology-driven construction and bioinformatics validation of a multi-epitope vaccine against Brucella spp. [PDF]

Sci Rep
Chai ZL, Qi XX, Li R, Luo JR, Li C, Shi HD, Tian TT, Shang KY, Zhu YJ, Zhang FB.   +9 more
europepmc   +1 more source

Design and evaluation of a multi-epitope HIV-1 vaccine based on human parvovirus virus-like particles

David Pérez-Saucedo, Nancy Vanessa Castro-Perea, Antonio Ruíz-Cruz, Ismael Bustos‐Jaimes, Mónica Viveros-Rogel, Leonor Huerta-Hernández, Leticia Moreno‐Fierros   +6 more
openalex   +1 more source

Multi Epitope Vaccine Prediction Against Aichi Virus using Immunoinformatic Approach [PDF]

, 2019
Asma Ali Hassan Ali, Sahar Abdeen Abdalla Mohamed, Marwa Abdulrahman Omer Musa, Amani Faisal Bushra ELtahier, Walaa Mohammed Alsamani Abdelrahman Ali, Elaf Ahmed Mohammed Ali Ibrahim, Ahmed Hamdi, Mohamed A. Hassan   +7 more
openalex   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Development and protective efficacy of multi-epitope vaccine FL46 against cystic echinococcosis. [PDF]

Front Immunol
Jiang T, Mahemuti M, Wang W, Han S, Wu X, Liu H, Chen Q, Mo X, Wang X, Kadiaili A, Hu Y, Cao J, Li S.   +12 more
europepmc   +1 more source

Multi-epitope vaccine design against human metapneumovirus via reverse vaccinology and molecular modelling. [PDF]

Sci Rep
Bukhari K.
europepmc   +1 more source