Results 251 to 260 of about 3,636,379 (304)

Generation and Evaluation of a Multi-Epitope Vaccine Against <i>Acinetobacter baumannii</i>, a Nosocomial Bacterial Pathogen. [PDF]

Vaccines (Basel)
Prather ND, Aki J, Jeffreys S, Arulanandam BP, Hung CY, Yu JJ.   +5 more
europepmc   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Immunoinformatics-based design and evaluation of a multi-epitope vaccine against Vibrio fluvialis. [PDF]

Sci Rep
Naveed M, Husnain M, Aziz T, Qadir P, Asim M, Majeed MN, Aloufi AS, Shami A, Alwethynani MS, Tombozara N.   +9 more
europepmc   +1 more source

Deniers and Compliers: Unpacking the Heterogeneous Effectiveness of U.S. Stay‐at‐Home Mandates During the COVID‐19 Pandemic

Journal of Applied Econometrics, EarlyView.
ABSTRACT While existing work shows COVID‐19 stay‐at‐home (SAH) policies decreased mobility on average, we lack evidence regarding heterogeneity in policy effectiveness across US counties. To uncover potential heterogeneity, we implement a novel two‐stage approach.
James Sears, Sofia B. Villas‐Boas, Molly Sears, Carly Trachtman, Linlin Fan, Andrew W. Stevens   +5 more
wiley   +1 more source

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang, Binbin Ge, Ming Li, Xiaochun Xia, Fuming Zhang, Pengqin Xu   +5 more
wiley   +1 more source

Design of a Multi-Epitope Vaccine Against Ovine <i>Pasteurella multocida</i> Using Immunoinformatics Strategies. [PDF]

Microorganisms
Qiao Y, Wu A, Li H, Zhuang Y, Fu Q, Yang L, Shi H.   +6 more
europepmc   +1 more source

Immunoinformatics approach to engineer a multi-epitope vaccine against SdrG in skin commensal Staphylococcus epidermidis. [PDF]

PLoS One
Akter S, Silva GVR, Oliveira JIN, Fulco UL, Xu X, Fu YV.   +5 more
europepmc   +1 more source

In silico design of the multi-epitope vaccine for lung adenocarcinoma based on hub gene-derived neoantigens. [PDF]

BMC Cancer
Li S, Huang M, Jia L, Liu S, Sun X, Cai D, Su Y, Chen M, Lu C, Huang J, Tu J, Ji J.   +11 more
europepmc   +1 more source

Immunoinformatic-guided design of a polo-like kinase 1 (PLK1)-targeted multi-epitope vaccine with preliminary <i>in vitro</i> validation. [PDF]

Front Bioinform
Munieswaran G, Subramani NK, Rajan AP, Manickam V.   +3 more
europepmc   +1 more source