Results 261 to 270 of about 3,636,379 (304)
Designing a chimeric multi-epitope vaccine against Candida auris using reverse vaccinology approach targeting the agglutinin-like protein N-terminal domain. [PDF]
Sci RepAljumaa MA +7 more
europepmc +1 more source
A pangenome-based strategy for designing a multi-epitope vaccine against non-toxin antigens of necrotic enteritis-associated Clostridium perfringens. [PDF]
Braz J MicrobiolGreco JPG +4 more
europepmc +1 more source
Multi-Epitope-Based Vaccine Candidate for Monkeypox: An In Silico Approach
Vaccines, 2022 Currently, there are limited treatment options available for the monkeypox disease. We used a computational strategy to design a specific antigenic vaccine against pathogens. After using various immunoinformatic tools and filters, cytotoxic T-cell lymphocyte (CTL)-, helper T-cell lymphocyte (HTL)-, and interferon gamma (IFN-γ)-inducing epitopes, which ...
Amena Ali +2 more
exaly +4 more sources
Development of a novel multi-epitope vaccine for brucellosis prevention
HeliyonBrucellosis, a zoonotic disease caused by Brucella, presents a significant threat to both animal and human health. In animals, the disease can lead to infertility, miscarriage, and high fever, while in humans, symptoms may include recurrent fever, fatigue, sweating, hepatosplenomegaly, and joint and muscle pain following infection.
Jianbing Ding +2 more
exaly +4 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Immunoinformatics Protocol to Design Multi-Epitope Subunit Vaccines
2023With the development of scientific technologies, the accessibility of genomic data, computational tools, software, databases, and machine learning, the field of immunoinformatics has emerged as an effective technique for immunologists to design potential vaccines in a short time.
Parismita, Kalita +2 more
openaire +2 more sources
A candidate multi‐epitope vaccine against Lumpy skin disease
Transboundary and Emerging Diseases, 2022Lumpy skin disease (LSD) is a fulminant infectious disease that mostly affects cattle and causes considerable economic loss throughout the globe. This study was conducted to develop a new multi-epitope-based vaccine against LSD that can elicit immunological responses using an in silico reverse vaccinology approach.
Md Bashir Uddin +10 more
openaire +2 more sources
Immunology & Cell Biology, 1997
The evolution of vaccine strategies has seen a move from whole organisms to recombinant proteins, and further towards the ultimate in minimalist vaccinology, the epitope. The epitope‐based approach is clearly compelling as only a relatively tiny, but immunologically relevant, sequence is often capable of inducing protective immunity against a large and
openaire +2 more sources
The evolution of vaccine strategies has seen a move from whole organisms to recombinant proteins, and further towards the ultimate in minimalist vaccinology, the epitope. The epitope‐based approach is clearly compelling as only a relatively tiny, but immunologically relevant, sequence is often capable of inducing protective immunity against a large and
openaire +2 more sources
Design of multi-epitope, analogue-based cancer vaccines
Expert Opinion on Biological Therapy, 2003The current objective of our cancer programme is to develop an effective vaccine based on rationally designed T cell epitope analogues, for use in the adjuvant setting for non-small cell lung cancer (NSCLC) and colon cancer. Analogue epitopes, enhanced for either human leukocyte antigen (HLA) binding or T cell receptor (TCR) signalling, have been shown
John D, Fikes, Alessandro, Sette
openaire +2 more sources
Evaluation of multi-epitope recombinant protein as a candidate for a contraceptive vaccine
Journal of Reproductive Immunology, 2021Contraceptive vaccine (CV) is a valuable, non-invasive, and alternative method for purposeful contraception. Sperm antigens are useful targets for producing CVs due to their specialized expression in sperm. In this study, a recombinant protein containing three main sperm epitopes (IZUMO1, SACA3, and PH-20) was designed and evaluated as CV to control ...
Behnam Mortazavi +4 more
openaire +2 more sources
Biologicals, 2001
We have developed efficient methods for epitope identification and vaccine design. Our process for epitope selection based on the combined use of motif analyses, binding assays and immunogenicity evaluations is described. We also describe how the projected population coverage and vaccine design can be optimized.
A, Sette +7 more
openaire +2 more sources
We have developed efficient methods for epitope identification and vaccine design. Our process for epitope selection based on the combined use of motif analyses, binding assays and immunogenicity evaluations is described. We also describe how the projected population coverage and vaccine design can be optimized.
A, Sette +7 more
openaire +2 more sources