Results 61 to 70 of about 11,461,097 (250)
IEEE AccessThe flywheel energy storage system, as an efficient and environmentally friendly energy storage method, has broad application prospects in areas such as grid peak regulation and integration of new energy sources.
Xiankui Wen +8 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Coupling Miniaturized Free-Flow Electrophoresis to Mass Spectrometry via a Multi-Emitter ESI Interface [PDF]
, 2020 We present a novel multi-emitter electrospray ionization interface for the coupling of microfluidicfree-flow electrophoresis (μFFE) with mass spectrometry.
Dirk, Janasek +4 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
AIP AdvancesThis study established a piezoelectric nanobeam model that considers surface effects, the action of a magnetic field, high-order electric fields, and the constraints of the Winkler–Pasternak linear elastic foundation, and then, the electromechanical ...
BaiQiang Liu, Peng Wang, XiaoTong Peng
doaj +1 more source
Research on Downhole Throttling Characteristics of Gas Wells Based on Multi-Field and Multi-Phase
, 2023 The formation of natural gas hydrates seriously affects the production efficiency of gas wells. Obtaining the correct temperature and pressure profile along the wellbore of gas wells is a prerequisite for accurately predicting the location of hydrate ...
Yihua Dou +5 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Thermoelastic vibration analysis of disc brake based on multi-physical field coupling method [PDF]
, 2020 Thermoelastic vibration is the main cause of brake jitter and noise, including significant fluctuations in temperature, thermal stress, structure size and braking moment.
Jian Zhang, Sen Zhang
core +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
EnergiesIn the operation of enhanced geothermal systems (EGSs), complex physical and chemical coupling processes, which are crucial for the efficient exploitation of geothermal energy, are involved.
Peng Xiao +8 more
doaj +1 more source