Results 41 to 50 of about 11,461,097 (250)
Axiomatic principle of multi field coupling dynamics analysis
, 2023 A multi-field coupling system involves several physical quantities and is usually difficult to achieve satisfactory performance in practice due to the lack of merit index for such complex system.
Zhang, Jinghui +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Research progress and prospect of multi-field coupling of coal seam mining
采矿与岩层控制工程学报A thorough understanding of the dynamic interaction and synergistic evolution mechanisms of stress, seepage, temperature, and chemical fields under mining disturbances is of great significance for ensuring the safe and efficient extraction of coal ...
Pengxiang ZHAO +8 more
doaj +1 more source
A parallelized model for coupled phase field and crystal plasticity simulation [PDF]
Computer Methods in Materials Science, 2016 The predictive simulation of materials with strong interaction between microstructural evolution and mechanical deformation requires the coupling of two or more multi-physics models.
Mingxuan Lin, Ulrich Prahl
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Study on the Deposition Characters of Linear Multi nozzle NFES to Direct write Aligned Nanofibers
Journal of Harbin University of Science and Technology, 2020 Nearfield electrospinning (NFES) directwriting of linear multinozzle is a highly efficient electrohydrodynamic technique for massvolume fabricating micronano structures.
WANG Zhifeng +6 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Research on associated motion simulation method and platform of control rod driving mechanism
Advances in Mechanical Engineering, 2021 The motion simulation analysis of the control rod drive mechanism is a typical multi-disciplinary cross-coupling problem covering electromagnetic field, flow field, and dynamic field.
Hongbiao Sun +4 more
doaj +1 more source
Temperature Field Simulation Analysis of Common Rail Injector Based on Multi-Field Coupling
, 2019 : The reliability of high pressure common rail injector depends on the calculation accuracy of its temperature changing. Due to the temperature measurement limitation and difficulty, in order to obtain more detailed temperature distribution, a coupling
An, Qingsong +5 more
core +1 more source