Results 61 to 70 of about 802,053 (235)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-Focus Color Image Fusion Algorithm Based on Super-Resolution Reconstruction and Focused Area Detection

open access: yesIEEE Access, 2020
Multi-focus image fusion is an image processing that generates an integrated image by merging multiple images from different focus area in the same scene. For most fusion methods, the detection of the focus area is a critical step.
Shuaiqi Liu   +6 more
doaj   +1 more source

Efficient Compressive Multi-Focus Image Fusion

open access: yesJournal of Computer and Communications, 2014
Two key points of pixel-level multi-focus image fusion are the clarity measure and the pixel coeffi- cients fusion rule. Along with different improvements on these two points, various fusion schemes have been proposed in literatures. However, the traditional clarity measures are not designed for compressive imaging measurements which are maps of ...
Chao Yang, Bin Yang
openaire   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

MULTIFOCUS IMAGE FUSION USING CLOUD MODEL [PDF]

open access: yesICTACT Journal on Image and Video Processing, 2014
This paper proposes a multifocus image fusion algorithm based on cloud model. First, each source images are divided into overlapping image blocks of size (2N+1) × (2N+1) and then the mean and entropy of every image pixels over this neighborhood window ...
K. Kannan
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multi-objective optimization and gray association for multi-focus image fusion

open access: yesJournal of Algorithms & Computational Technology, 2016
Multi-objective optimization and gray association are classical technologies in intelligent system. In this paper, a novel multi-focus image fusion method based on the technology is proposed.
Suli Wang, Xiaoqing Luo
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Multi focus acoustic field generation using Dammann gratings for phased array transducers

open access: yesResults in Physics
Phased array transducers can shape acoustic fields for versatile manipulation; however, generating multiple focal points typically involves complex optimization.
Tatsuki Fushimi, Yusuke Koroyasu
doaj   +1 more source

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