Results 61 to 70 of about 8,371,948 (295)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Multi-focus and Multi-window Techniques for Interactive Network Exploration

open access: yes, 2018
Networks analysts often need to compare nodes in different parts of a network. When zoomed to fit a computer screen, the detailed structure and node labels of even a moderately-sized network (say, with 500 nodes) can become invisible or difficult to read.
Ted Selker (5428499)   +2 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Editorial: Letter from Editors

open access: yes, 2021
Dear Focus on ELT Journal Readers, As we all know, selecting an appropriate publication outlet for scholarly work is a crucial decision. In this context, we believe that Focus on ELT Journal is the right outlet for potential contributions to the field of
Başal, Ahmet   +2 more
core   +1 more source

Algebraic Multi-Grid Based Multi-Focus Image Fusion Using Watershed Algorithm

open access: yesIEEE Access, 2018
This paper proposes a new multi-focus image fusion method named AMGW, and it is based on algebraic multi-grid (AMG) algorithm and watershed segmentation method.
Ying Huang   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Greater Easterhouse multi-agency domestic violence forum: report on multi-agency day conference 22nd September 1998, Eastbank Health Promotion Centre [PDF]

open access: yes, 1998
This report provides highlights and delegate feedback from Greater Easterhouse Multi-Agency Domestic Violence Forum conference held September 1998. This brought together over 60 delegates from key agencies, representing a spread of senior managers and ...
Greater Easterhouse Multi-Agency Domestic Violence Forum
core   +1 more source

Conducting Cross-Cultural, Multi-Lingual and Multi-Country Focus Groups: Guidance for Researchers

open access: yesInternational Journal of Qualitative Methods, 2021
Conducting cross-cultural, multi-lingual and multi-country focus groups represents unique logistic and analytical challenges. However, there is little guidance for the necessary considerations required for such international focus groups.
Mariana Pinto da Costa
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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