Results 61 to 70 of about 1,507,774 (276)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Interest Points as a Focus Measure in Multi-Spectral Imaging [PDF]
A novel multi-spectral focus measure that is based on algorithms for interest point detection, particularly on the FAST (Features from Accelerated Segment Test), Fast Hessian and Harris-Laplace detector, is described in this paper.
Cika, P. +3 more
core +1 more source
Image Coaddition with Temporally Varying Kernels
Large, multi-frequency imaging surveys, such as the Large Synaptic Survey Telescope (LSST), need to do near-real time analysis of very large datasets. This raises a host of statistical and computational problems where standard methods do not work.
A. C. Becker +9 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A Geometric Dictionary Learning Based Approach for Fluorescence Spectroscopy Image Fusion
In recent years, sparse representation approaches have been integrated into multi-focus image fusion methods. The fused images of sparse-representation-based image fusion methods show great performance.
Zhiqin Zhu +3 more
doaj +1 more source
Accuracy of Shack-Hartmann wavefront sensor using a coherent wound fibre image bundle
Shack-Hartmann wavefront sensors using wound fibre bundles are desired for multi-object adaptive optical systems to provide large multiplex positioned by Starbugs.
Goodwin, Michael +2 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Sample Distortion for Compressed Imaging
We propose the notion of a sample distortion (SD) function for independent and identically distributed (i.i.d) compressive distributions to fundamentally quantify the achievable reconstruction performance of compressed sensing for certain encoder-decoder
Davies, Mike E., Guo, Chunli
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

