Results 111 to 120 of about 630,412 (304)

Multi Generations in the Workforce: Building Collaboration

IIMB Management Review, 2012
AbstractOrganisations the world over in today's rapid growth context are faced with the challenge of understanding a multi-generational workforce and devising policies and processes to build collaboration between them. In its first part, this article synthesises the literature on generational studies, with emphasis on the definition of generations and ...
openaire   +3 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Enabling target-aware molecule generation to follow multi objectives with Pareto MCTS

Communications Biology
Target-aware drug discovery has greatly accelerated the drug discovery process to design small-molecule ligands with high binding affinity to disease-related protein targets.
Yaodong Yang, Guangyong Chen, Jinpeng Li, Junyou Li, Odin Zhang, Xujun Zhang, Lanqing Li, Jianye Hao, Ercheng Wang, Pheng-Ann Heng   +9 more
doaj   +1 more source

Experimental and CFD analysis of rotary multi vane expander for small capacity generation

MATEC Web of Conferences, 2018
Every year, Indonesia's population increase so as energy demand. To fulfill Indonesia's energy needs, the capacity of energy production should be increased.
Mahardika Mohammad
doaj   +1 more source

Multi-generation genomic prediction of maize yield using parametric and non-parametric sparse selection indices. [PDF]

Heredity (Edinb), 2021
Lopez-Cruz M, Beyene Y, Gowda M, Crossa J, Pérez-Rodríguez P, de Los Campos G.   +5 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

ClipFaceFusion multi modal diffusion for high fidelity facial generation and modification

Scientific Reports
The generation of photorealistic human faces utilizing multi-modal inputs presents significant challenges, as existing methodologies like DiffusionCLIP are limited to text-based directives and often struggle with precise attribute control and cross-modal
Xueming Jiang, Yi Ding
doaj   +1 more source

Genomic selection models substantially improve the accuracy of genetic merit predictions for fillet yield and body weight in rainbow trout using a multi-trait model and multi-generation progeny testing. [PDF]

Genet Sel Evol, 2023
Garcia A, Tsuruta S, Gao G, Palti Y, Lourenco D, Leeds T.   +5 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Family aggregation of sleep characteristics: Results of the Heinz Nixdorf Recall and the Multi-Generation Study. [PDF]

PLoS One, 2021
Kowall B, Lehnich AT, Schramm S, Schmidt B, Erbel R, Jöckel KH, Stang A.   +6 more
europepmc   +1 more source