Results 141 to 150 of about 630,412 (304)

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

A multi model orchestrated agent for live flight and hotel itinerary generation

Discover Artificial Intelligence
The evolution of large language models into autonomous, goal-oriented systems capable of advanced reasoning, contextual memory recall, and dynamic tool orchestration is referred to as agentic AI. This work introduces an intelligent travel companion built
B. Nethravathi, Pooja Gupta, C. P. Lalitha Shree, S. Srivatsa, G. N. Harshith, Sudharani   +5 more
doaj   +1 more source

Intergenerational transmission of child maltreatment using a multi-informant multi-generation family design. [PDF]

PLoS One, 2020
Buisman RSM, Pittner K, Tollenaar MS, Lindenberg J, van den Berg LJM, Compier-de Block LHCG, van Ginkel JR, Alink LRA, Bakermans-Kranenburg MJ, Elzinga BM, van IJzendoorn MH.   +10 more
europepmc   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Correction: Intergenerational transmission of child maltreatment using a multi-informant multi-generation family design. [PDF]

PLoS One, 2020
Buisman RSM, Pittner K, Tollenaar MS, Lindenberg J, van den Berg LJM, Compier-de Block LHCG, van Ginkel JR, Alink LRA, Bakermans-Kranenburg MJ, Elzinga BM, van IJzendoorn MH.   +10 more
europepmc   +1 more source

"What we owe our children, they their children, and..." [PDF]

Egalitarian theorists, since Rawls, have in the main advocated equalizing some objective standard of individual well-being, such as primary goods, functioning, or resources, rather than subjective welfare.
John Roemer
core  

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Using whole-genome SNP data to reconstruct a large multi-generation pedigree in apple germplasm. [PDF]

BMC Plant Biol, 2020
Muranty H, Denancé C, Feugey L, Crépin JL, Barbier Y, Tartarini S, Ordidge M, Troggio M, Lateur M, Nybom H, Paprstein F, Laurens F, Durel CE.   +12 more
europepmc   +1 more source

Population aging and the extended family in Taiwan [PDF]

Population aging produces changes in the availability of kin with uncertain implications for extended living arrangements. We propose a highly stylized model that can be used to analyze and project age-specific proportions of adults living in extended ...
Andrew Mason, Sang-Hyop Lee
core