Results 51 to 60 of about 630,412 (304)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Combined Scheduling and Configuration Optimization of Power-to-Methanol System Considering Feedback Control of Thermal Power

Energies
A power-to-methanol (P2M) system is a promising energy storage approach in transforming surplus renewable energy into a chemical product while utilizing the captured CO2 from conventional thermal power units.
Junjie Ye, Yinghui Liu, Li Sun, Ke Chen
doaj   +1 more source

Multi-generational benefits of genetic rescue

Scientific Reports
AbstractGenetic rescue—an increase in population fitness following the introduction of new alleles—has been proven to ameliorate inbreeding depression in small, isolated populations, yet is rarely applied as a conservation tool. A lingering question regarding genetic rescue in wildlife conservation is how long beneficial effects persist in admixed ...
Dave P. Onorato, Mark W. Cunningham, Mark Lotz, Marc Criffield, David Shindle, Annette Johnson, Bambi C. F. Clemons, Colin P. Shea, Melody E. Roelke-Parker, Warren E. Johnson, Brett T. McClintock, Kristine L. Pilgrim, Michael K. Schwartz, Madan K. Oli   +13 more
openaire   +3 more sources

Editorial [PDF]

, 2009
This article does not have a description. This article is hosted by our co-publisher Taylor & Francis. For the full table of contents for this and previous issues of this journal, please visit the Gender and Development ...
Sweetman, C., Vera-Sanso, Penny
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-Generation Model of Immigrant Earnings: Theory and Application [PDF]

, 2001
The literature, starting with Chiswick (1977, 1978) to Gang and Zimmermann (2000), more recently, focuses on the economic achievements and performance of first- and secondgeneration migrants.
Epstein, Gil S., Lecker, Tikva
core  

The history of video quality model validation [PDF]

, 2013
C
Pinson, M, Staelens, Nicolas, Webster, A
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Paraphrase Generation Model Integrating Transformer Architecture, Part-of-Speech Features, and Pointer Generator Network

IEEE Access, 2023
In recent years, hardware advancements have enabled natural language processing tasks that were previously difficult to achieve due to their intense computing requirements.
Yu-Chia Tsai, Feng-Cheng Lin
doaj   +1 more source