Results 61 to 70 of about 630,412 (304)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Arbitrary multi-qubit generation
New Journal of Physics, 2016 We propose and analyse a scheme for single-rail-encoded arbitrary multi-qubit quantum-state generation to provide a versatile tool for quantum optics and quantum information applications.
F Shahandeh +3 more
doaj +1 more source
Non-mammalian model organisms in epigenetic research : an overview [PDF]
, 2020 Recent advances in sequencing technology and genome editing tools had an indisputably enormous impact on our understanding of complex biological pathways and their genetic and epigenetic regulation.
Baruah, Sri Kartik +3 more
core +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Neuropsychiatric Disease and Treatment, 2021 Benjamin Kearns, Katy Cooper, Anna Cantrell, Chloe Thomas School of Health and Related Research, The University of Sheffield, Sheffield, UKCorrespondence: Benjamin Kearns Email b.kearns@sheffield.ac.ukPurpose: Cardiovascular and metabolic adverse events ...
Kearns B, Cooper K, Cantrell A, Thomas C
doaj
Investigations of organic food and health [PDF]
, 2003 Numerous studies have attempted to elucidate if there is a difference in the effect on human health, between food produced according to the organic standards compared with conventionally produced food.
Brandt, Dr. Kirsten +1 more
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Multi-generalized 2-normed space
Filomat, 2017 In this paper, we introduce the concepts of multi-generalized 2-normed space and dual multigeneralized 2-normed space and we then investigate some results related to them. We also prove that, if (E,||.,.||) is a generalized 2-normed space, {||.,.||k}k?N is a sequence of generalized 2-norms on Ek (k ? N) such that for each x,y ? E, ||x,y||1 =
Khanehgir, Mahnaz +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source