Results 1 to 10 of about 9,485,608 (197)

A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour‐targeting function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier, Sandra Szu‐Wei Hwang, Anthony F. Rullo   +2 more
wiley   +1 more source

Variational autoencoders for regression: recovering fully leptonic b b ¯ W + W − $$ b\overline{b}{W}^{+}{W}^{-} $$ in di-Higgs searches

Journal of High Energy Physics
The search for double Higgs production in b b ¯ W + W − $$ b\overline{b}{W}^{+}{W}^{-} $$ , where both W bosons decay to leptons, has been rehabilitated as a good option to investigate key processes within the Standard Model scalar sector at the LHC. The
Alexandre Alves, Eduardo da Silva Almeida, Igor Neiva Mesquita   +2 more
doaj   +1 more source

Women in business: Gender and commercial space in nineteenth‐century Glasgow

The Economic History Review, EarlyView.
Abstract Focusing on women entrepreneurs in a large British city, we examine how women's commercially listed businesses populated that city. Using commercial property rental records, our study allows us to understand sectoral variation and the distribution of businesses across the city and to assess both the absolute and relative contribution of women ...
Graeme Acheson, Gill Newton, Linda Perriton   +2 more
wiley   +1 more source

Balancing efficiency and robustness in project team formation: a hybrid evolutionary‐MCDM approach

International Transactions in Operational Research, EarlyView.
Abstract Effective team formation requires balancing technical skills, personality compatibility, and project constraints when selecting small teams from large candidate pools. Traditional multi‐criteria decision‐making (MCDM) methods provide rigorous evaluation but face scalability limitations.
Georgios Stavrou, Panagiotis Adamidis, Jason Papathanasiou   +2 more
wiley   +1 more source

Enhancing the sensitivity for triple Higgs boson searches with deep learning techniques

Journal of High Energy Physics
Using two benchmark models containing extended scalar sectors beyond the Standard Model, we study deep learning techniques to enhance the sensitivity of resonant triple Higgs boson searches in the fully hadronic 6b channel, which suffers from the ...
Cheng-Wei Chiang, Feng-Yang Hsieh, Shih-Chieh Hsu, Zhi-Zhong Li, Ian Low   +4 more
doaj   +1 more source

Nurses' Scope of Practice in Home‐Based Care: An Observational Study of Care Activities, Clinical Decision‐Making, and Contextual Modulators—The DECIDE Project

Journal of Clinical Nursing, EarlyView.
ABSTRACT Background and Aim Nurses' scope of practice is central to healthcare delivery. While scope of practice is well described conceptually, there is limited empirical research capturing how it is enacted in everyday clinical practice. This study aimed to describe scope of practice in home‐based care, focusing on care activities, clinical decision ...
Ida Røed Flyum, Gunilla Borglin, Anna Josse Eklund, Veronica Pavedahl, Edith Roth Gjevjon   +4 more
wiley   +1 more source

GOOFy fermions

Journal of High Energy Physics
A new class of symmetries, named GOOFy symmetries of two Higgs doublet models, was recently discovered, the result of an unorthodox transformation on scalar and gauge fields and spacetime coordinates. It was explicitly shown that it is possible to choose
P. M. Ferreira
doaj   +1 more source

Two Higgs Doublets, a 4th Generation and a 125 GeV Higgs: A Review

Advances in High Energy Physics, 2013
We review the possible role that multi-Higgs models may play in our understanding of the dynamics of a heavy 4th sequential generation of fermions. We describe the underlying ingredients of such models, focusing on two Higgs doublets, and discuss how ...
Shaouly Bar-Shalom, Michael Geller, Soumitra Nandi, Amarjit Soni   +3 more
doaj   +1 more source

‘The Simpsons’ Did It Again! Periodontitis and Tooth Loss Predict Mortality in Springfield: A Retrospective Cohort Study

Journal of Periodontal Research, EarlyView.
The IMPOSTERS study analysed 150 recurring ‘human’ Simpsons characters and found that periodontitis or tooth loss was associated with a 23‐fold higher hazard of all‐cause mortality. This was reported in the Simpsons universe, with the death of ‘Bleeding Gums’ Murphy, 3 years before the first such reports in our universe.
Praveen Sharma, Thomas Dietrich
wiley   +1 more source

Reconstruction of boosted and resolved multi-Higgs-boson events with symmetry-preserving attention networks

Journal of High Energy Physics
The production of multiple Higgs bosons at the CERN LHC provides a direct way to measure the trilinear and quartic Higgs self-interaction strengths as well as potential access to beyond the standard model effects that can enhance production at large ...
Haoyang Li, Marko Stamenkovic, Alexander Shmakov, Michael Fenton, Darius Shih-Chieh Chao, Kaitlyn Maiya White, Caden Mikkelsen, Jovan Mitić, Cristina Mantilla Suarez, Melissa Quinnan, Greg Landsberg, Harvey Newman, Pierre Baldi, Daniel Whiteson, Javier Duarte   +14 more
doaj   +1 more source