Results 41 to 50 of about 1,394,686 (289)
How state-reinforced knowledge infrastructure influences adaptive urban water governance
Ecology and SocietyResilience and environmental governance scholars have long studied and debated the role of the state in driving or coordinating responses to the varied dimensions of adaptive governance.
Aaron Deslatte +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Cognitive instabilities under contention, friction, and the fog-of-war challenge the AI revolution
Connection Science, 2020 The asymptotic limit theorems of information theory, and related formalism from punctuated equilibrium evolutionary theory, allow exploration of the dynamics of real-time, multi-component, hierarchical, cognitive enterprises – institutional, machine, or ...
Rodrick Wallace
doaj +1 more source
Co-designing climate-smart farming systems with local stakeholders: A methodological framework for achieving large-scale change [PDF]
, 2019 The literature is increasing on how to prioritize climate-smart options with stakeholders but relatively few examples exist on how to co-design climate-smart farming systems with them, in particular with smallholder farmers.
Acosta Alba, Ivonne +8 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Community resilience to multi-hazard risks: Insights from Narayani Basin, Nepal
Progress in Disaster ScienceNepal's diverse topography and changing climate expose communities to interconnected multi-hazard risks, including floods, landslides, storms, and earthquakes.
Prakriti Niraula +2 more
doaj +1 more source
The green economy, sustainability transitions and transition regions : a case study of Boston [PDF]
, 2014 This paper is focused upon exploring the development of the green economy in particular locations, with the aim of identifying why some cities and regions have been successful in engendering green growth.
Gibbs, David, O'Neill, Kirstie
core +3 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Sustainable EnvironmentThe management of empty pesticide containers (EPCs) poses not only an environmental challenge but also a complex organizational and institutional issue, necessitating coordinated efforts across government, industry, and agricultural communities. Improper
Lailafitri Handayani +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source