Results 51 to 60 of about 1,432 (217)

FedIHRAS: A Privacy-Preserving Federated Learning Framework for Multi-Institutional Collaborative Radiological Analysis with Integrated Explainability and Automated Clinical Reporting

Biomedicines
Background/Objectives: Federated learning has emerged as a promising paradigm for enabling collaborative artificial intelligence in healthcare while preserving data privacy.
André Luiz Marques Serrano, Gabriel Arquelau Pimenta Rodrigues, Guilherme Dantas Bispo, Vinícius Pereira Gonçalves, Geraldo Pereira Rocha Filho, Maria Gabriela Mendonça Peixoto, Rodrigo Bonacin, Rodolfo Ipolito Meneguette   +7 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Spatiotemporal Evolution and Mechanism of Environmental Governance in the Pearl River Delta from the Perspective of Global-Local Interactions

Redai dili
In the context of ecological civilization construction and high-quality development, exploring the mechanisms of local environmental governance transformation under globalization is of substantial academic significance for understanding regional ...
Jiangmin Yang, Gengzhi Huang, Jili Xu, Desheng Xue   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Algorithmic inclusion? The role of AI-assisted inclusive leadership in shaping gendered outcomes in multicultural academic teams

Frontiers in Psychology
Artificial Intelligence (AI) adoption across Higher Education Institutions (HEIs) has gained considerable momentum, and is now being used for faculty recruitment, promotion, workload allocation, research impact evaluation and student assessments ...
Iram Tahir, M. Sebnem Ensari, Khuram Shahzad, Rahat G. Kazmi, Rahat G. Kazmi, Ahmad Abu Arja   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Legal coordination and governance approaches for transboundary water resources management in the Greater Bay Area

Discover Environment
The Guangdong–Hong Kong–Macao Greater Bay Area (GBA), a major Chinese economic hub, faces growing water governance challenges stemming from transboundary geography, uneven resource distribution, and differentiated administrative systems under the “one ...
Ziqing Yan
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

From single property rights to nested property rights: beyond the traditional natural resource property rights paradigm

Ecology and Society
This study addresses the growing complexity of natural resource governance by moving beyond conventional property rights paradigms. Focusing on rangeland management practices in four pastoral communities on the Qinghai-Tibetan Plateau (QTP) in China, the
Yingjun Qi, Xiangyu Jia
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source