Results 81 to 90 of about 1,432 (217)

The effectiveness of using participatory evaluation in enhancing institutional performance: a case study from the United Arab Emirates

Frontiers in Education
IntroductionParticipatory evaluation has gained attention as a collaborative approach to institutional assessment, promoting shared decision-making and stakeholder engagement.
Ahmed Elhakim
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

AGRI-TECH AND LIVESTOCK MANAGEMENT: ECONOMIC AND POLICY DRIVERS OF DIGITAL ADOPTION IN NIGERIA AND SOUTH AFRICA

Ayika
The usage of digital technologies in the agricultural sector is becoming widely recognised as a means of enhancing efficiency, productivity, and sustainability in developing countries.
Olukayode Idris Lasisi, Bisiriyu Abiodun Taleat, Muslim Akinbola Akintola, Kedibone Phago   +3 more
doaj   +1 more source

Multi Institutional Semi-Structured Learning Environments [PDF]

Journal of Systemics, Cybernetics and Informatics, 2013
A description of two effective and novel collaborative learning environments that support engineering and technological innovation is provided. While offering great value to systems, and systems of systems, engineering practice, these environments are ...
Raymond R. Buettner Jr.
doaj  

A multi‐institutional multi‐methods analysis of jeopardy systems in academic hospital medicine

Journal of Hospital Medicine
AbstractBackgroundHospital medicine programs use backup (“jeopardy”) systems to cover unexpected staffing gaps, but little is known about their structures or optimal practices.ObjectivesTo describe jeopardy structures, assess clinician perceptions, and identify potential approaches across a broad sample of hospital medicine groups.MethodsThis multi ...
Kirsten N. Kangelaris, Angela Keniston, Andrew D. Auerbach, Gregory Bowling, Marisha Burden, Shradha A. Kulkarni, Luci K. Leykum, Anne S. Linker, Matthew Sakumoto, Jeffrey Schnipper, Gopi Astik   +10 more
openaire   +2 more sources

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Protocol for an open-source system to integrate calcium imaging, pupillometry, and locomotion-estimated tracking in head-fixed mice

STAR Protocols
Summary: A wide selection of behavioral assays in systems neuroscience relies on head-fixation protocols to integrate in vivo multi-photon imaging approaches.
Maria M. Ortiz-Juza, Jovan Tormes-Vaquerano, Sophia M. Hegel, Vincent R. Curtis, Rizk A. Alghorazi, Noah W. Miller, Ellora M. McTaggart, Nicolas C. Pégard, Jose Rodriguez-Romaguera   +8 more
doaj   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

A protocol for acquiring high-quality single-cell multi-omics data from human peripheral blood

STAR Protocols
Summary: Single-cell analysis of human peripheral blood cells provides insights into innate and adaptive immune systems. However, robust protocols are essential to ensuring single-cell sequencing data quality and cell viability.
Shanshan Duan, Guokang Ma, Junjie Chen, Xuyang Shi, Zishuo Yuan, Wenwen Zhou, Qiuting Deng, Yang Wang, Jianhua Yin, Yue Yuan, Chuanyu Liu   +10 more
doaj   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source