Results 91 to 100 of about 14,787,075 (288)

Political Disagreement and Delegation in a Multi-Level Governance Setting [PDF]

open access: yes
A large share of delegation models takes into account the effect of political disagreement when explaining delegation. Yet, delegation models make sharply contrasting predictions on how political disagreement translates into the level of discretion ...
Diane Payne   +2 more
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

A Multi-level Perspective on Policy Composition

open access: yes
Abstract The expectation of the superiority of a design approach to public policy-making is based on the expectation that a well-conceived, well-crafted, and well-executed policy design can drive effective policy performance and outcomes better than one which is not.
Giliberto Capano, Michael Howlett
openaire   +1 more source

Sensorless Control of a Fault-tolerant Multi-level PMSM Drive [PDF]

open access: yes, 2018
This paper presents a new technique to track the saliency position in a permanent magnet synchronous motor (PMSM) post a single phase open-circuit fault.
Mark Sumner   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Empowerment and adult education

open access: yesEuropean Journal for Research on the Education and Learning of Adults
Empowerment, as a goal of adult education, seeks to support people to critically reflect on structural settings and to take constructive action towards social equality and social change. This article analyses empowerment and adult education from a micro-
Julia Saam, Regina Egetenmeyer
doaj   +1 more source

EU Transport Infrastructure Policy, New Institutionalism and Types of Multi-Level Governance: The Case of Vienna [PDF]

open access: yes, 2009
Multi-level Governance (MLG) fundamentally challenges a state-centric, intergovernmentalist understanding of EU policy-making, emphasising the nonhierarchical, interconnected and multi-actor nature of contemporary governing.
Awesti, Anil
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Multiple energy benefits from regional policy programs within Europe – a social construction perspective

open access: yesFrontiers in Energy Efficiency
The benefits of energy efficiency (EE) improvements in industry include multiple energy benefits (MEBs) that have not been studied extensively. Although MEBs are assumed to result from energy efficiency measures (EEMs), they have not been examined ...
Noor Jalo   +4 more
doaj   +1 more source

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