Results 81 to 90 of about 650,905 (306)
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Political Disagreement and Delegation in a Multi-Level Governance Setting [PDF]
A large share of delegation models takes into account the effect of political disagreement when explaining delegation. Yet, delegation models make sharply contrasting predictions on how political disagreement translates into the level of discretion ...
Diane Payne +2 more
core
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Adolescents’ values of children and their future plans to have children: A multi-level perspective
, 2008 The value-of-children approach relates reasons for having children (= values of children, VOCs) to fertility behavior. Several studies have shown that on the cultural as well as on the individual level economic-utilitarian VOCs are related to higher ...
Trommsdorff, Gisela, Mayer, Boris
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
, 2022 reservedIn Italy, in 2020 1.3 million children live in absolute poverty. A number which has kept growing in the past decade and which got worse due to the Covid-19 pandemic. Research shows how investing in children is a crucial strategy to promote a fair
CODDA, GRETA SOPHIE
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Sustainability: Science, Practice, & Policy, 2020 City logistics as a research field offers a wide range of potential solutions and technologies for advancing toward modern and sustainable mobility. As societies demand environments that are more ecological and cities tackle the effects of growing e ...
Tim Fraske, Bernd Bienzeisler
doaj +1 more source
, 2003 The reallocation of authority upwards, downwards, and sideways from central states has drawn attention from a growing number of scholars in political science.
Marks, Gary, Hooghe, Liesbet
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DESIRE: Modelling Multi-Agent Systems in a Compositional Formal Framework [PDF]
, 1997 This paper discusses an example of the application of a high-level modelling framework which enables both the specification and implementation of a system's conceptual design.
Jennings, N. R. +11 more
core +1 more source