Results 61 to 70 of about 14,787,075 (288)

Adolescents’ values of children and their future plans to have children: A multi-level perspective [PDF]

open access: yes, 2008
The value-of-children approach relates reasons for having children (= values of children, VOCs) to fertility behavior. Several studies have shown that on the cultural as well as on the individual level economic-utilitarian VOCs are related to higher ...
Trommsdorff, Gisela, Mayer, Boris
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Learning Multi-View Representations with Graph-Level Fusion: A Bi-Level Optimization Perspective

open access: yesBig Data and Cognitive Computing
Multi-view representation learning, aiming to extract discriminative patterns from heterogeneous data sources, has attracted increasing attention in recent years.
Na Song   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Multi-level model outputs.

open access: yes, 2022
Multi-level model outputs.
Claudien Razafiarimanana (14232018)   +1 more
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

A theory-based decision support framework for energy transition: pluralized perspective

open access: yesFrontiers in Sustainability
This study presents a theory-based decision support framework for energy transitions that addressed the requirement for comprehensive approach beyond routine problem-solving techniques.
Olaoluwa Paul Aasa   +3 more
doaj   +1 more source

Energy Modelling as a Trigger for Energy Communities: A Joint Socio-Technical Perspective

open access: yesEnergies, 2020
Mainstreaming energy communities has been one of the main challenges in the low-carbon transition of cities. In this sense, urban building energy modelling (UBEM) has an untapped role in enabling energy communities, as simulations on urban models provide
Viktor Bukovszki   +4 more
doaj   +1 more source

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