Results 61 to 70 of about 650,905 (306)
Multi-level simulation of a BEV using EMR methodology
, 2020 International audienceThe automotive industry is shifting to mass production of electrified vehicles. Simulation is a key step for developing these new vehicles. System simulation tools as Simcenter Amesim includes ready-to-use multi-physics libraries in
Matthieu PONCHANT +21 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Europeanisation at the Urban Level: Local Actors, Institutions and the Dynamics of Multi-Level Interaction [PDF]
, 2004 Involvement in EU-sponsored programmes has provided urban institutions and actors across Europe with unprecedented access to new sources of information, legitimacy, and not least, financial support.
Marshall, Adam Jay., Adam Jay Marshall
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A Multi-perspective and Multi-level Based Approach to Organize and Represent Inventive Knowledge
, 2019 Part 3: TRIZ Applications in Technical DesignInternational audienceThrough analyzing the solving mechanism of product inventive design problem based on TRIZ theory, we propose in this paper a multi-perspective and multi-level knowledge organization model,
Longfan Liu +5 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Ecology and SocietyAgroecology has been proposed as an answer to the current global agri-food system crises. Transformation to agroecological agri-food systems can be enhanced through collaboration between societal agroecological initiatives and scientists in reflexive ...
Pauline Cassart +7 more
doaj +1 more source
Agriculture, 2019 The multi-level perspective (MLP) is a prominent transition framework. The MLP posits that transitions come about through interaction processes within and among three analytical levels: niches, socio-technical regimes and a socio-technical landscape ...
Hamid El Bilali
doaj +1 more source
When Europe Hits City Hall: The Europeanization of Cities in the EU Multi-level System [PDF]
, 2007 [From the introduction] Although local politics is increasingly shaped by EU decisions, the Europeanization of cities has only emerged as a topic for analysis recently (John 2000; Marshall 2005; Kassim 2005: 303-307).
Kern, Kristine.
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