Results 111 to 120 of about 2,361,025 (277)

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Innovative interventions in support of innovation networks. A complex system perspective to public innovation policy and private technology brokering [PDF]

open access: yes
The linear model of innovation has been superseded by a variety of theoretical models that view the innovation process as systemic, complex, multi-level, multi-temporal, involving a plurality of heterogeneous economic agents. Accordingly, the emphasis of
Federica Rossi   +3 more
core  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

A multi-level approach for supporting configurations: A new perspective on software product line engineering [PDF]

open access: yes, 2017
Configuration is a common way in many markets to cope with reduc- ing costs and improving customer satisfaction. There are various approaches to represent product configurations, the most common of which is feature model- ing.
Clark, Tony   +3 more
core  

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Infrastructure Transitions in Southern Cities: Organising Urban Service Delivery for Climate and Development

open access: yesUrban Planning
Rapidly growing cities in the Global South are characterised by high levels of vulnerability and informality and are expected to bear a disproportionate share of the costs of a changing climate.
Lucy Oates, Andrew Sudmant
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Empirical application of the multi-level perspective: tracing the history of ground-source heat pumps systems in Finland

open access: yesSustainability: Science, Practice, & Policy, 2019
The emergence and evolution of more sustainable technologies and related industrial fields is a core concern for sustainability transitions scholars.
Ville Lauttamäki, Sampsa Hyysalo
doaj   +1 more source

Mod\'elisation multi-niveaux dans AA4MM [PDF]

open access: yes, 2012
In this article, we propose to represent a multi-level phenomenon as a set of interacting models. This perspective makes the levels of representation and their relationships explicit.
Bourjot, Christine   +3 more
core   +3 more sources

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