Results 121 to 130 of about 5,967,457 (249)

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

open access: yesAdvanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang   +15 more
wiley   +1 more source

Magnetic Laboratory Exterior

open access: yes, 1902
Magnetic Laboratory with electric poles in front and lines entering the ...
unknown
core   +3 more sources

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren   +11 more
wiley   +1 more source

Fault tolerant homopolar magnetic bearings

open access: yes, 2005
A magnetic bearing for supporting a spinning shaft in the radial direction and/or the axial direction includes a rotor formed on the shaft and a stator positioned around the rotor. Poles in the stator creates a magnetic field that supports the rotor. The
Li, Ming-hsiu   +7 more
core   +1 more source

m5C Reader ALYREF Promotes the Progression of Endometrial Cancer by Activating the XRCC6‐Mediated Wnt/β‐catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study identifies ALYREF as an oncogenic m5C reader in endometrial cancer. ALYREF recognizes NSUN2‐mediated m5C modification on XRCC6 mRNA to enhance transcript stability and increase XRCC6 expression. Elevated XRCC6 activates Wnt/β‐catenin signaling, resulting in accelerated tumor cell proliferation, migration, invasion, and xenograft tumor growth.
Linlin Hao   +8 more
wiley   +1 more source

Comparative assessment of a novel 8/18 multi-teeth with conventional 8/10 in-wheel SRM for an E-Scooter

open access: yesAutomatika
Electric scooters are increasingly gaining popularity in India owing to rising global crude oil prices and rising levels of vehicular pollution. Most of them are currently powered by expensive in-wheel (IW) permanent magnet (PM) brushless DC motors ...
B Sandesh Bhaktha   +5 more
doaj   +1 more source

Probabilistic Computing via Gate‐Tunable Random Telegraph Noise

open access: yesAdvanced Science, EarlyView.
Intrinsic random telegraph noise in metal–oxide–semiconductor field‐effect transistors is harnessed to create gate‐tunable probabilistic bits. By modulating carrier‐trapping dynamics, the device produces stochastic binary outputs with a continuous bias‐to‐probability transfer.
Gyungwon Yun   +8 more
wiley   +1 more source

Analysis on The Magnetic Damper with Opposite Poles by Turns [PDF]

open access: yes, 2017
application/pdfJournal ArticleA magnetic damper in which opposite poles are arranged by turns has great deal of damping effects as compared with a normal magnetic damper.
長屋, 幸助, 8248, 8247, 関口, 肇
core  

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung   +15 more
wiley   +1 more source

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

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