Results 41 to 50 of about 919,462 (268)
FermentationThis study presents the production, characterization, and potential pharmaceutical application of a bioemulsifier synthesized by Aspergillus niger UCP 1064 by submerged fermentation using agro-industrial residues (cassava wastewater and soluble starch ...
Uiara Maria de Barros Lira Lins +2 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Digital fabrication of multi-material biomedical objects [PDF]
Biofabrication, 2009 This paper describes a multi-material virtual prototyping (MMVP) system for modelling and digital fabrication of discrete and functionally graded multi-material objects for biomedical applications. The MMVP system consists of a DMMVP module, an FGMVP module and a virtual reality (VR) simulation module.
Choi, SH, Cheung, HH
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Novel Hybrid Manufacturing Process of CM247LC and Multi-Material Blisks
Micromachines, 2020 The study on CM247LC used the traditional approach for Near-Netshape Hot Isostatic Pressing (NNSHIP) with sacrificial low carbon steel tooling, which was built using Selective Laser Melting (SLM), to produce a shaped CM247LC blisk.
Xiqian Wang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Ballistic response mechanism and resistance-driven evaluation method of UHMWPE composite
Defence TechnologyThe use of ultra-high molecular weight polyethylene (UHMWPE) composite in the design of lightweight protective equipment, has gained a lot of interest.
Yemao He +5 more
doaj +1 more source
Additive Manufacturing Letters, 2023 This study compares the tensile response of laser powder bed fusion (LPBF) fabricated Hastelloy X (HX) coupons with those of conventionally manufactured HX over the temperature range of 22-800°C and strain rate of 10−4-10−2 s−1.
X Li +6 more
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Dreidimensionale Multi-Material-Bauteile
, 2023 Das Ziel des Projekts besteht darin, neue Fertigungsansätze zu erarbeiten, die das Laserstrahlschmelzen von Kunststoffen mit dem elektrophotographischen Pulverauftrag kombinieren, um thermoplastische Multi-Material-Bauteile herzustellen. Der Einsatz der Elektrophotographie ermöglicht eine schnelle und hochpräzise Präparation von Multi-Material ...
Kopp, Sebastian-Paul, Roth, Stephan
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