Results 31 to 40 of about 88,926 (217)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Mathematical approach for rapid determination of pull-in displacement in MEMS devices

Frontiers in Physics
IntroductionMicroelectromechanical systems (MEMS) are pivotal in diverse fields such as telecommunications, healthcare, and aerospace. A critical challenge in MEMS devices is accurately determining the pull-in displacement and voltage, which ...
Yongcun Shao, Yutong Cui
doaj   +1 more source

Dual-Layer Fusion Knowledge Reasoning with Enhanced Multi-modal Features [PDF]

Jisuanji kexue yu tansuo
Most of the existing multi-modal knowledge reasoning methods use splicing or attention to directly fuse the multi-modal features extracted from the pre-trained model, often ignoring the heterogeneity and interaction complexity between different modes ...
JING Boxiang, WANG Hairong, WANG Tong, YANG Zhenye
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Revealing neural resonance in neuronal ensembles through frequency response tests

Scientific Reports
Photobiomodulation emerges as a novel method to boost neuronal activities and brain function, with notable implications for treating brain disorders.
Peng Zhang, Liuye Yao, Tianyi Yang, Yajun Lou, Wei Xu, Wei Jiang, Weitao Li, Xiaofei Ji, Fan Gao, Zhiyu Qian   +9 more
doaj   +1 more source

An Adaptive Acoustic Recognition System for Low-Altitude Airspace Security Based on Decoupled Dynamic Frequency Bands and Random Sound Sources

Algorithms
The acoustic frequency fingerprint (AFF) for drone recognition has emerged as a flexible and practical approach to address low-altitude airspace security concerns.
Miyi Zeng, Tingxiu Chen, Cao Huang, Fengyi Zhang, Yulong Ji   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Practice and proficiency of Isha Yoga for better mental health outcomes: insights from a COVID-19 survey

Frontiers in Public Health
IntroductionThe COVID-19 pandemic has brought about unparalleled suffering on a global scale, affecting both physical and mental well-being. In such challenging times, it becomes crucial to identify interventions that can alleviate negative mental health
Saketh Malipeddi, Seema Mehrotra, John P. John, Bindu M. Kutty   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source