Results 51 to 60 of about 596,735 (263)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

External archive guided radial-grid multi objective differential evolution

Scientific Reports
Differential evolution (DE) is a robust evolutionary algorithm for solving single-objective and multi-objective optimization problems (MOPs). While numerous multi-objective DE (MODE) variants exist, prior research has primarily focused on parameter ...
Vikas Palakonda, Samira Ghorbanpour, Jae-Mo Kang, Heechul Jung   +3 more
doaj   +1 more source

Multi objective optimization of microalgae flat plate photobioreactor design

E3S Web of Conferences, 2018
Indonesia as a maritime country has high potential in developing microalgae. Microalgae in Indonesia have a high oil component of around 20-30%, for example Nitzschia palea (23%), Chlorella vulgaris (27%), and Euglena gracilis (20%).
Rahman Arif, Nasution Sanjaya BS, Siregar Sri RH, Nasruddin   +3 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Optimasi Produksi Hijab Menggunakan Program Linear Multi Objective Fuzzy

Jambura Journal of Mathematics, 2019
Beberapa penelitian tentang optimalisasi produksi sudah dilakukan, salah satu metode yang sering digunakan adalah metode simpleks. Namun, metode ini memiliki keterbatasan, diantaranya hanya dapat digunakan pada kasus yang memiliki satu fungsi tujuan ...
Rima Erfianti, Muhamad Nizam Muhaijir
doaj   +1 more source

Multi Objective Based Framework for Energy Management of Smart Micro-Grid

IEEE Access, 2020
The increasing demand of energy in the traditional grids is getting more complex, less feasible, harmful, uneconomical and high in power losses. This paper presents an efficient energy management approach to mitigate such issues with smart micro grid ...
Muhammad Haseeb, Syed Ali Abbas Kazmi, M. Mahad Malik, Sajid Ali, Syed Basit Ali Bukhari, Dong Ryeol Shin   +5 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Multi‐objective decision‐making for road design

Transport, 2008
Multi‐objective analysis is a popular tool to solve many economic, managerial and construction problems. The objective of this research is to develop and implement a methodology for multi‐objective optimization of multi‐alternative decisions in road ...
Willem Karel M. Brauers, Edmundas Kazimieras Zavadskas, Friedel Peldschus, Zenonas Turskis   +3 more
doaj  

Multi‐Objective Optimisation Framework for Heterogeneous Federated Learning

CAAI Transactions on Intelligence Technology
Federated learning is a distributed framework that trains a centralised model using data from multiple clients without transferring that data to a central server.
Jamshid Tursunboev, Vikas Palakonda, Il‐Min Kim, Sunghwan Moon, Jae‐Mo Kang   +4 more
doaj   +1 more source