Results 71 to 80 of about 633,451 (264)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Multi‐objective decision‐making for road design
Transport, 2008 Multi‐objective analysis is a popular tool to solve many economic, managerial and construction problems. The objective of this research is to develop and implement a methodology for multi‐objective optimization of multi‐alternative decisions in road ...
Willem Karel M. Brauers +3 more
doaj
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Multi‐Objective Optimisation Framework for Heterogeneous Federated Learning
CAAI Transactions on Intelligence TechnologyFederated learning is a distributed framework that trains a centralised model using data from multiple clients without transferring that data to a central server.
Jamshid Tursunboev +4 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Multi-object spectroscopy in space
SPIE Proceedings, 1998 From the scientific objectives of the Next Generation Space Telescope, this paper tries to constrain the design of the NGST Multi-Object Spectrograph. Several technical alternatives are presented that could address the requirements of the Design Reference Mission.
Burgarella, D. +4 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
METAHEURISTIC-DRIVEN MULTI OBJECTIVE FIR FILTER DESIGN FOR ECG DENOISING
International Journal of Advances in Signal and Image SciencesDigital signal processing in biomedical applications requires advanced filtering techniques that can simultaneously optimize multiple performance criteria.
Mehmet Fatih Karakaş, Fatma Latifoğlu
doaj +1 more source