Results 51 to 60 of about 815,587 (296)

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

MultiMiTar: a novel multi objective optimization based miRNA-target prediction method. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Machine learning based miRNA-target prediction algorithms often fail to obtain a balanced prediction accuracy in terms of both sensitivity and specificity due to lack of the gold standard of negative examples, miRNA-targeting site context ...
Ramkrishna Mitra   +1 more
doaj   +1 more source

Optimized multi-objective design of herringbone micromixers [PDF]

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009)   +2 more
core  

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Multi-Objective Calibration For Agent-Based Models [PDF]

open access: yes, 2004
Agent-based modelling is already proving to be an immensely useful tool for scientific and industrial modelling applications. Whilst the building of such models will always be something between an art and a science, once a detailed model has been built ...
Rogers, Alex, von Tessin, Peter
core  

Multi-Objective Big Data Optimization with jMetal and Spark [PDF]

open access: yes, 2017
Big Data Optimization is the term used to refer to optimization problems which have to manage very large amounts of data. In this paper, we focus on the parallelization of metaheuristics with the Apache Spark cluster computing system for solving multi ...
A Cabanas-Abascal   +11 more
core   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Multi-objective design of robust flight control systems [PDF]

open access: yes, 2008
A multi–objective evolutionary algorithm is used in the framework of H1 control theory to find the controller gains that minimize a weighted combination of the infinite–norm of the sensitivity function (for disturbance attenuation requirements) and ...
Avanzini, G.   +3 more
core   +3 more sources

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

A benchmark generator for dynamic multi-objective optimization problems [PDF]

open access: yes, 2014
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Many real-world optimization problems appear to not only have multiple objectives that conflict each other ...
Jiang, Jiang, Shouyong, Yang, Shengxiang
core   +1 more source

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