Optimization of train real-time dynamic scheduling under unexpected events in high-speed railway based on MAPPO. [PDF]
Tang Z, Huang P, Sun J.
europepmc +1 more source
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley +1 more source
A two-phase optimization approach in designing sustainable hospital menus by integrating nutrition, cost, and environmental factors. [PDF]
Ehsanitabar F +6 more
europepmc +1 more source
CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang +11 more
wiley +1 more source
A Load-Balancing-Aware Learning Framework for Collaborative UAV-MEC Computation Offloading. [PDF]
Li H +7 more
europepmc +1 more source
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li +6 more
wiley +1 more source
Optimized scheduling of integrated energy systems: a multi-dimensional electricity, hydrogen, ammonia, heat synergy approach using the LSDBO-WOA algorithm. [PDF]
Tu N, Yang J, Yan X, Fan Z.
europepmc +1 more source
Correcting the apparent priming effect resolves systematic biases in Asian rice fertilizer nitrogen accounting. Net soil retention drops below 7%, while 48% of fertilizer escapes, inflicting US$98.53 billion in annual reactive‐nitrogen damages. High‐resolution mapping uncovers N‐risk archetypes across 42% of the rice area, delivering a spatially ...
Xiuyun Liu +5 more
wiley +1 more source
Student Perspectives on a Smoothie-Based Educational Program Designed Using Social Cognitive Theory and Choice Architecture. [PDF]
Sullivan A +7 more
europepmc +1 more source
The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source

